Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus
infection, mediating the transcriptional induction of type I interferons and other genes that …

Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are RNA sensor molecules that
play essential roles in innate antiviral immunity. Among the three RLRs encoded by the …

The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

Background Gut microbiota-derived short-chain fatty-acid (SFCA) acetate protects mice
against RSV A2 strain infection by increasing interferon-β production and expression of …

The COVID‐19 pandemic caused relatively high mortality in patients, especially in those
with concomitant diseases (ie, diabetes, hypertension, and chronic obstructive pulmonary …

During viral infection, virus-derived cytosolic nucleic acids are recognized by host
intracellular specific sensors. The efficacy of this recognition system is crucial for triggering …

Abstract The current Coronavirus Disease 2019 (COVID-19) pandemic, caused by the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …

Human respiratory syncytial virus (RSV) is the most important cause of acute lower
respiratory tract disease in infants worldwide. As a first line of defense against respiratory …

Re-emerging and new viral pathogens have caused significant morbidity and mortality
around the world, as evidenced by the recent monkeypox, Ebola and Zika virus outbreaks …

RIG-I-like receptors (RLRs) are crucial for pathogen detection and triggering immune
responses and have immense physiological importance. In this review, we first summarize …