Cell adhesion to the extracellular matrix is fundamental to tissue integrity and human health.
Integrins are the main cellular adhesion receptors that through multifaceted roles as …

Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

TrackMate is an automated tracking software used to analyze bioimages and is distributed
as a Fiji plugin. Here, we introduce a new version of TrackMate. TrackMate 7 is built to …

Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …

Efficient clearance of dying cells (efferocytosis) is an evolutionarily conserved process for
tissue homeostasis. Genetic enhancement of efferocytosis exhibits therapeutic potential for …

Enzymatically-degradable materials recapitulate the dynamic and reciprocal interactions
between cells and their native microenvironment by allowing cells to actively shape the …

The ability of cells to migrate is a fundamental physiological process involved in embryonic
development, tissue homeostasis, immune surveillance, and wound healing. Therefore, the …

Abstract 2D surfaces offer simple analysis of cells in culture, yet these often yield different
cell morphologies and responses from those observed in vivo. Considerable effort has …

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer. During invasion, the
encapsulating DCIS basement membrane (BM) is compromised, and tumor cells invade the …

The ability of cells to migrate is a fundamental physiological process involved in embryonic
development, tissue homeostasis, immune surveillance and wound healing. In order for …