The meiotic checkpoint network: step-by-step through meiotic prophase

VV Subramanian… - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
The generation of haploid gametes by meiosis is a highly conserved process for sexually
reproducing organisms that, in almost all cases, involves the extensive breakage of …

Crossover interference: shedding light on the evolution of recombination

SP Otto, BA Payseur - Annual review of genetics, 2019 - annualreviews.org
Through recombination, genes are freed to evolve more independently of one another,
unleashing genetic variance hidden in the linkage disequilibrium that accumulates through …

The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo

NR Powers, ED Parvanov, CL Baker, M Walker… - PLoS …, 2016 - journals.plos.org
In many mammals, including humans and mice, the zinc finger histone methyltransferase
PRDM9 performs the first step in meiotic recombination by specifying the locations of …

[HTML][HTML] A familial study of azoospermic men identifies three novel causative mutations in three new human azoospermia genes

M Gershoni, R Hauser, L Yogev, O Lehavi, F Azem… - Genetics in …, 2017 - Elsevier
Purpose Up to 1% of all men experience azoospermia, a condition of complete absence of
sperm in the semen. The mechanisms and genes involved in spermatogenesis are mainly …

Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro

X Zhang, S Gunewardena, N Wang - Nature communications, 2021 - nature.com
The molecular machinery and chromosome structures carrying out meiosis are frequently
conserved from yeast to mammals. However, signals initiating meiosis appear divergent …

RPA homologs and ssDNA processing during meiotic recombination

J Ribeiro, E Abby, G Livera, E Martini - Chromosoma, 2016 - Springer
Meiotic homologous recombination is a specialized process that involves homologous
chromosome pairing and strand exchange to guarantee proper chromosome segregation …

Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice

S Yamada, S Kim, SE Tischfield, M Jasin, J Lange… - Cell Cycle, 2017 - Taylor & Francis
The SPO11-generated DNA double-strand breaks (DSBs) that initiate meiotic recombination
occur non-randomly across genomes, but mechanisms shaping their distribution and repair …

Control of meiotic double-strand-break formation by ATM: local and global views

A Lukaszewicz, J Lange, S Keeney, M Jasin - Cell Cycle, 2018 - Taylor & Francis
ABSTRACT DNA double-strand breaks (DSBs) generated by the SPO11 protein initiate
meiotic recombination, an essential process for successful chromosome segregation during …

Mammalian meiotic recombination: a toolbox for genome evolution

L Capilla, M Garcia Caldés… - Cytogenetic and Genome …, 2016 - karger.com
Meiotic recombination is a process that increases genetic diversity and is fundamental for
sexual reproduction. Determining by which mechanisms genetic variation is generated and …

Investigating the potential of X chromosome shredding for mouse genetic biocontrol

MD Bunting, GI Godahewa, NO McPherson… - Scientific Reports, 2024 - nature.com
CRISPR-Cas9 technology has facilitated development of strategies that can potentially
provide more humane and effective methods to control invasive vertebrate species, such as …