Network-based drug repositioning: approaches, resources, and research directions

S Alaimo, A Pulvirenti - Computational methods for drug repurposing, 2019 - Springer
The wealth of knowledge and omic data available in drug research allowed the rising of
several computational methods in drug discovery field yielding a novel and exciting …

[HTML][HTML] Proteochemometrics–recent developments in bioactivity and selectivity modeling

BJ Bongers, AP IJzerman, GJP Van Westen - Drug Discovery Today …, 2019 - Elsevier
Proteochemometrics is a machine learning based modeling approach relying on a
combination of ligand and protein descriptors. With ongoing developments in machine …

Joint imbalanced classification and feature selection for hospital readmissions

G Du, J Zhang, Z Luo, F Ma, L Ma, S Li - Knowledge-Based Systems, 2020 - Elsevier
Hospital readmission is one of the most important service quality measures. Recently,
numerous risk assessment models have been proposed to address the hospital readmission …

Multi-label learning with label-specific features by resolving label correlations

J Zhang, C Li, D Cao, Y Lin, S Su, L Dai, S Li - Knowledge-Based Systems, 2018 - Elsevier
In multi-label learning, different labels may have their own inherent characteristics for
distinguishing each other, in the meanwhile, exploiting the correlations among labels is …

A cost-sensitive attention temporal convolutional network based on adaptive top-k differential evolution for imbalanced time-series classification

X Zhang, H Peng, J Zhang, Y Wang - Expert Systems with Applications, 2023 - Elsevier
Imbalanced time-series classification (ITSC) is ubiquitous in many real-world applications. In
this study, a novel cost-sensitive deep learning framework, namely ACS-ATCN, is proposed …

SANE: a sequence combined attentive network embedding model for COVID-19 drug repositioning

X Su, Z You, L Wang, L Hu, L Wong, B Ji, B Zhao - Applied Soft Computing, 2021 - Elsevier
The COVID-19 has now spread all over the world and causes a huge burden for public
health and world economy. Drug repositioning has become a promising treatment strategy …

Kernelized fuzzy rough sets based online streaming feature selection for large-scale hierarchical classification

S Bai, Y Lin, Y Lv, J Chen, C Wang - Applied Intelligence, 2021 - Springer
In recent years, many online streaming feature selection approaches focus on flat data,
which means that all data are taken as a whole. However, in the era of big data, not only the …

Learning from class-imbalance and heterogeneous data for 30-day hospital readmission

G Du, J Zhang, S Li, C Li - Neurocomputing, 2021 - Elsevier
Predicting 30-day hospital readmission is a core research task in the development of
personalized healthcare. However, the imbalanced class distribution and the heterogeneity …

Towards graph-based class-imbalance learning for hospital readmission

G Du, J Zhang, F Ma, M Zhao, Y Lin, S Li - Expert Systems with Applications, 2021 - Elsevier
Predicting hospital readmission with effective machine learning techniques has attracted a
great attention in recent years. The fundamental challenge of this task stems from …

Online hierarchical streaming feature selection based on adaptive neighborhood rough set

T Shu, Y Lin, L Guo - Applied Soft Computing, 2024 - Elsevier
In the era of open machine learning, a kind of data is accompanied by a hierarchical
structure between classes in the label space and the increasing number of features …