Valvular heart disease is a major cause of morbidity and mortality worldwide. Surgical valve
repair or replacement has been the standard of care for patients with valvular heart disease …

Wound dressings are traditionally used to protect a wound and to facilitate healing.
Currently, their function is expanding. There is an urgent need for new smart products that …

Cutaneous fibrosis results from suboptimal wound healing following significant tissue injury
such as severe burns, trauma, and major surgeries. Pathologic skin fibrosis results in scars …

Somatic cells that change from one mature phenotype to another exhibit the property of
plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this …

Scar formation is a major medical problem that can have devastating consequences for
patients. The adverse physiological and psychological effects of scars are broad, and there …

Significance: Excessive scarring is major clinical and financial burden in the United States.
Improved therapies are necessary to reduce scarring, especially in patients affected by …

It is clear that the well-described phenomenon of epithelial–mesenchymal transition (EMT)
plays a pivotal role in embryonic development, wound healing, tissue regeneration, organ …

The development and application of decellularized extracellular matrices (ECM) has grown
rapidly in the fields of cell biology, tissue engineering and regenerative medicine in recent …

This textbook describes the basic principles of induced organ regeneration in skin and
peripheral nerves and extends the original successful paradigm to other organs. A set of …

Cutaneous wound healing is a complex process with many types of mechanical forces
regulating the quality and speed of healing. The role of mechanical forces in regulating …