Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases
G Tardiolo, P Bramanti, E Mazzon - Molecules, 2018 - mdpi.com
N-acetylcysteine (NAC), which is an acetylated cysteine compound, has aroused scientific
interest for decades due to its important medical applications. It also represents a nutritional …
interest for decades due to its important medical applications. It also represents a nutritional …
Hypoxia-inducible factor-1: Regulatory mechanisms and drug development in stroke
Z Pan, G Ma, L Kong, G Du - Pharmacological research, 2021 - Elsevier
Stroke is an acute cerebrovascular disease caused by sudden rupture of blood vessels in
the brain or blockage of blood vessels, which has now become one of the main causes of …
the brain or blockage of blood vessels, which has now become one of the main causes of …
Deciphering the iron side of stroke: neurodegeneration at the crossroads between iron dyshomeostasis, excitotoxicity, and ferroptosis
N DeGregorio-Rocasolano, O Martí-Sistac… - Frontiers in …, 2019 - frontiersin.org
In general, iron represents a double-edged sword in metabolism in most tissues, especially
in the brain. Although the high metabolic demands of brain cells require iron as a redox …
in the brain. Although the high metabolic demands of brain cells require iron as a redox …
The potential for natural antioxidant supplementation in the early stages of neurodegenerative disorders
F Oppedisano, J Maiuolo, M Gliozzi… - International journal of …, 2020 - mdpi.com
The neurodegenerative process is characterized by the progressive ultrastructural
alterations of selected classes of neurons accompanied by imbalanced cellular …
alterations of selected classes of neurons accompanied by imbalanced cellular …
Neurotoxicity of zinc
DR Morris, CW Levenson - Neurotoxicity of metals, 2017 - Springer
Zinc-induced neurotoxicity has been shown to play a role in neuronal damage and death
associated with traumatic brain injury, stroke, seizures, and neurodegenerative diseases …
associated with traumatic brain injury, stroke, seizures, and neurodegenerative diseases …
Berberine inhibits the ischemia-reperfusion induced testicular injury through decreasing oxidative stress
Purpose The aim of this study was to investigate the effect of berberine (BBR) on oxidative
stress in an experimental testicular I/R injury model. Methods Eighteen rats were divided into …
stress in an experimental testicular I/R injury model. Methods Eighteen rats were divided into …
Ethyl pyruvate improves white matter remodeling in rats after traumatic brain injury
L Mao, L Sun, J Sun, B Sun, Y Gao… - CNS Neuroscience & …, 2021 - Wiley Online Library
Background Severe traumatic brain injury (TBI) results in long‐term neurological deficits
associated with white matter injury (WMI). Ethyl pyruvate (EP) is a simple derivative of the …
associated with white matter injury (WMI). Ethyl pyruvate (EP) is a simple derivative of the …
Effect of ethyl pyruvate on oxidative state and endoplasmic reticulum stress in a rat model of testicular torsion
We investigated the effects of ethyl pyruvate (EP) on oxidative and endoplasmic reticulum
(ER) stress due to experimental testicular ischemia-reperfusion (IR). Eighteen rats were …
(ER) stress due to experimental testicular ischemia-reperfusion (IR). Eighteen rats were …
N-acetylcysteine protects testicular tissue against ischemia/reperfusion injury via inhibiting endoplasmic reticulum stress and apoptosis
Background In animal models, endoplasmic reticulum (ER) stress has been reported to play
a vital role in mediating ischemia/reperfusion (I/R) injury in certain organs, such as brain …
a vital role in mediating ischemia/reperfusion (I/R) injury in certain organs, such as brain …
[HTML][HTML] Antioxidants in experimental ischemia-reperfusion injury of the testis: where are we heading towards?
G Vaos, N Zavras - World journal of methodology, 2017 - ncbi.nlm.nih.gov
Testicular torsion (TT) is a medical emergency that primary affects newborns and young
adolescents. It causes testicular injury due to the torsion of the spermatic cord and its …
adolescents. It causes testicular injury due to the torsion of the spermatic cord and its …