Macrophage immunotherapy: overcoming impediments to realize promise

LM Sly, DM McKay - Trends in Immunology, 2022 - cell.com
As an essential component of immunity, macrophages have key roles in mammalian host
defense, tissue homeostasis, and repair, as well as in disease pathogenesis and …

The pharmacological evidence of the chang-yan-ning formula in the treatment of colitis

W Yu, Y Zhang, C Kang, Y Zheng, X Liu… - Frontiers in …, 2022 - frontiersin.org
Ulcerative colitis (UC) is a subtype of inflammatory bowel disease (IBD) and occurs mainly in
the colon. The etiology of UC is rather complex and involves various pathological factors …

E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis

Y Kajimura, A Taguchi, Y Nagao, K Yamamoto… - Communications …, 2024 - nature.com
Macrophages are versatile cells of the innate immune system that work by altering their pro-
or anti-inflammatory features. Their dysregulation leads to inflammatory disorders such as …