Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …
Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
S Patel - The Journal of steroid biochemistry and molecular …, 2018 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine disorder, afflicting females of
reproductive age. This syndrome leads to infertility, insulin resistance, obesity, and …
reproductive age. This syndrome leads to infertility, insulin resistance, obesity, and …
High cortisol and the risk of dementia and Alzheimer's disease: a review of the literature
Introduction: Cortisol effects on the brain are exerted through two distinct receptors, inducing
complex and even opposite effects on the cerebral structures implicated in the various …
complex and even opposite effects on the cerebral structures implicated in the various …
Peripheral markers of depression
A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …
medical and socioeconomic burden. There is a growing interest in the biological …
The role of the hypothalamus–pituitary–adrenal (HPA) axis in test-induced anxiety: assessments, physiological responses, and molecular details
JA Hinds, ER Sanchez - Stresses, 2022 - mdpi.com
Test anxiety may be a contributing factor to low-performing examination scores among
students. There can be numerous physiological responses in the body that lead to test …
students. There can be numerous physiological responses in the body that lead to test …
Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus
Controversy exists over the role of stress and depression in the pathophysiology of type 2
diabetes mellitus. Depression has been shown to increase the risk for progressive insulin …
diabetes mellitus. Depression has been shown to increase the risk for progressive insulin …
The future of rodent models in depression research
Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …
burden of this debilitating disorder is anticipated to increase markedly over the coming …
Stress and obesity: are there more susceptible individuals?
Abstract Purpose of Review Stress has long been suspected to be interrelated to
(abdominal) obesity. However, interindividual differences in this complex relationship exist …
(abdominal) obesity. However, interindividual differences in this complex relationship exist …
From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.
GM Slavich, MR Irwin - Psychological bulletin, 2014 - psycnet.apa.org
Major life stressors, especially those involving interpersonal stress and social rejection, are
among the strongest proximal risk factors for depression. In this review, we propose a …
among the strongest proximal risk factors for depression. In this review, we propose a …