[HTML][HTML] Insights into adenovirus host cell interactions from structural studies
GR Nemerow, L Pache, V Reddy, PL Stewart - Virology, 2009 - Elsevier
Human adenoviruses cause a significant number of acute respiratory, enteric and ocular
infections, however they have also served as useful model systems for uncovering …
infections, however they have also served as useful model systems for uncovering …
The influence of adenovirus fiber structure and function on vector development for gene therapy
The collective attributes of adenoviruses (Ads), including ease of accomplishing replication
deficiency, readily achievable high titers, encoding of large expression cassettes, efficiency …
deficiency, readily achievable high titers, encoding of large expression cassettes, efficiency …
Difference imaging of adenovirus: bridging the resolution gap between X‐ray crystallography and electron microscopy.
PL Stewart, SD Fuller, RM Burnett - The EMBO journal, 1993 - embopress.org
While X‐ray crystallography provides atomic resolution structures of proteins and small
viruses, electron microscopy provides complementary structural information on the …
viruses, electron microscopy provides complementary structural information on the …
A triple β-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous protein
Human adenoviruses are responsible for respiratory, gastro-enteric and ocular infections
and can serve as gene therapy vectors. They form icosahedral particles with 240 copies of …
and can serve as gene therapy vectors. They form icosahedral particles with 240 copies of …
Image reconstruction reveals the complex molecular organization of adenovirus
PL Stewart, RM Burnett, M Cyrklaff, SD Fuller - Cell, 1991 - cell.com
The three-dimensional structure of adenovirus has been determined by image
reconstruction from cryoelectron micrographs. Comparison with the high resolution X-ray …
reconstruction from cryoelectron micrographs. Comparison with the high resolution X-ray …
The structure of the human adenovirus 2 penton
The adenovirus penton, a noncovalent complex of the pentameric penton base and trimeric
fiber proteins, comprises the vertices of the adenovirus capsid and contains all necessary …
fiber proteins, comprises the vertices of the adenovirus capsid and contains all necessary …
Rabies virus glycoprotein is a trimer
Y Gaudin, RWH Ruigrok, C Tuffereau, M Knossow… - Virology, 1992 - Elsevier
The oligomerization state of the rabies virus envelope glycoprotein (G protein) was
determined using electron microscopy and sedimentation analysis of detergent solubilized …
determined using electron microscopy and sedimentation analysis of detergent solubilized …
Crystal structure of the receptor-binding domain of adenovirus type 5 fiberprotein at 1.7 Å resolution
D Xia, LJ Henry, RD Gerard, J Deisenhofer - Structure, 1994 - cell.com
Background: Adenoviral infection begins with the binding of virion to the surface of host
cells. Specific attachment is achieved through interactions between host-cell receptors and …
cells. Specific attachment is achieved through interactions between host-cell receptors and …
Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli
LJ Henry, DI Xia, ME Wilke, J Deisenhofer… - Journal of …, 1994 - Am Soc Microbiol
The adenovirus fiber protein is used for attachment of the virus to a specific receptor on the
cell surface. Structurally, the protein consists of a long, thin shaft that protrudes from the …
cell surface. Structurally, the protein consists of a long, thin shaft that protrudes from the …
[HTML][HTML] Crystal structure of reovirus attachment protein σ1 reveals evolutionary relationship to adenovirus fiber
JD Chappell, AE Prota, TS Dermody, T Stehle - The EMBO journal, 2002 - embopress.org
Reovirus attaches to cellular receptors with the σ1 protein, a fiber‐like molecule protruding
from the 12 vertices of the icosahedral virion. The crystal structure of a receptor‐binding …
from the 12 vertices of the icosahedral virion. The crystal structure of a receptor‐binding …