Melanoma is one of the most immunologic malignancies based on its higher prevalence in
immune‐compromised patients, the evidence of brisk lymphocytic infiltrates in both primary …

Introduction: Survivin (SVN) is a member of the inhibitor of apoptosis (IAP) protein family that
promotes cellular proliferation and inhibits apoptosis. Overexpression of SVN is associated …

Originally considered to act as a transcriptional co-factor, Pirin has recently been reported to
play a role in tumorigenesis and the malignant progression of many tumors. Here, we have …

CBP/p300 interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 (CITED1)
is a transcriptional activator belonging to the non-DNA-binding transcription co-regulator …

Simple Summary The v-raf murine sarcoma viral oncogene homolog B1 (BRAF) gene
containing a 15-base pair (bp) deletion at L485-P490 is the cause of several cancers. We …

Posttranslational modifications (PTMs) are essential mechanisms that provide chemical
diversity to proteins. The additional functional and structural elements can be introduced to …

The clinical outcome of BRAF-mutated advanced melanoma has been improved by both
molecular targeted therapies and immune checkpoint inhibitors. Long-term follow-up data …

Simple Summary The mutational load of BRAFV600E in melanomas has been described as
a possible prognostic biomarker but there is no information about the mutant allele …

Dear Editor, Our investigation into the mitochondrial proteome dynamics in metastatic
melanoma reveals profound metabolic reprogramming that is central to the progression and …

Mahogunin Ring Finger 1 (MGRN1), a ubiquitin ligase expressed in melanocytes, interacts
with the α melanocyte-stimulating hormone receptor, a well-known melanoma susceptibility …