Trefoil factors: initiators of mucosal healing
D Taupin, DK Podolsky - Nature reviews Molecular cell biology, 2003 - nature.com
Maintaining the integrity of the gastrointestinal tract, despite the continual presence of
microbial flora and injurious agents, is essential. Epithelial continuity depends on a family of …
microbial flora and injurious agents, is essential. Epithelial continuity depends on a family of …
Trefoil factors: Structure of mammalian trefoil factors and functional insights
L Thim, FEB May - Cellular and Molecular Life Sciences CMLS, 2005 - Springer
The present review will include the mammalian trefoil factors, TFF1, TFF2 and TFF3. It will
summarise the amino acid sequences from different species, their posttranslational …
summarise the amino acid sequences from different species, their posttranslational …
Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor
K Kinoshita, DR Taupin, H Itoh… - Molecular and cellular …, 2000 - Taylor & Francis
The trefoil peptide intestinal trefoil factor (ITF) plays a critical role in the protection of colonic
mucosa and is essential to restitution after epithelial damage. These functional properties …
mucosa and is essential to restitution after epithelial damage. These functional properties …
The estrogen‐regulated protein, TFF1, stimulates migration of human breast cancer cells
SJ Prest, FEB May, BR Westley - The FASEB Journal, 2002 - Wiley Online Library
The human trefoil protein TFF1 is a small cysteine‐rich secreted protein that is frequently
expressed in breast tumors under the control of estrogen. The function of TFF1 in breast …
expressed in breast tumors under the control of estrogen. The function of TFF1 in breast …
pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins
C Tomasetto, R Masson, JL Linares, C Wendling… - Gastroenterology, 2000 - Elsevier
Background & Aims: Trefoil factors (TFFs) are secreted gastrointestinal proteins that have
been shown to protect and promote healing of the gastrointestinal tract. Moreover, pS2/TFF1 …
been shown to protect and promote healing of the gastrointestinal tract. Moreover, pS2/TFF1 …
Trefoil factor family (TFF) peptides and cancer progression
S Emami, S Rodrigues, CM Rodrigue, N Le Floch… - Peptides, 2004 - Elsevier
TFF peptides are involved in mucosal maintenance and repair through motogenic and
antiapoptotic activities. These peptides are overexpressed during inflammatory processes …
antiapoptotic activities. These peptides are overexpressed during inflammatory processes …
The pS2/TFF1 trefoil factor, from basic research to clinical applications
S Ribieras, C Tomasetto, MC Rio - … et Biophysica Acta (BBA)-Reviews on …, 1998 - Elsevier
pS2/TFF1 trefoil factor is normally expressed in the stomach, and is found ectopically in
gastrointestinal inflammatory disorders and in various carcinomas. It is involved in stomach …
gastrointestinal inflammatory disorders and in various carcinomas. It is involved in stomach …
[HTML][HTML] Trefoil factors share a lectin activity that defines their role in mucus
The mucosal epithelium secretes a host of protective disulfide-rich peptides, including the
trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell …
trefoil factors (TFFs). The TFFs increase the viscoelasticity of the mucosa and promote cell …
Cell type specific expression of secretory TFF peptides: colocalization with mucins and synthesis in the brain
W Hoffmann, W Jagla - International review of cytology, 2002 - Elsevier
The “TFF domain” is an ancient cysteine-rich shuffled module forming the basic unit for the
family of secretory TFF peptides (formerly P-domain peptides and trefoil factors). It is also an …
family of secretory TFF peptides (formerly P-domain peptides and trefoil factors). It is also an …
Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1
WD Morgan, B Birdsall, TA Frenkiel… - Journal of molecular …, 1999 - Elsevier
The solution structure of the 96-residue C-terminal fragment of the merozoite surface protein
1 (MSP-1) from Plasmodium falciparum has been determined using nuclear magnetic …
1 (MSP-1) from Plasmodium falciparum has been determined using nuclear magnetic …