The biomedical use of silk: past, present, future

C Holland, K Numata… - Advanced healthcare …, 2019 - Wiley Online Library
Humans have long appreciated silk for its lustrous appeal and remarkable physical
properties, yet as the mysteries of silk are unraveled, it becomes clear that this outstanding …

Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside

D Chouhan, BB Mandal - Acta biomaterialia, 2020 - Elsevier
Silk biomaterials are known for biomedical and tissue engineering applications including
drug delivery and implantable devices owing to their biocompatible and a wide range of …

Recent advances in self-assembled peptides: Implications for targeted drug delivery and vaccine engineering

S Eskandari, T Guerin, I Toth, RJ Stephenson - Advanced drug delivery …, 2017 - Elsevier
Self-assembled peptides have shown outstanding characteristics for vaccine delivery and
drug targeting. Peptide molecules can be rationally designed to self-assemble into specific …

Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications

W Zhang, X Yu, Y Li, Z Su, KD Jandt, G Wei - Progress in Polymer Science, 2018 - Elsevier
The design and fabrication of self-assembled peptide nanostructures offer an amazing
platform for creating functional nanomaterials for various biomedical applications. Utilizing …

Tunable self-assembly of genetically engineered silk–elastin-like protein polymers

XX Xia, Q Xu, X Hu, G Qin, DL Kaplan - Biomacromolecules, 2011 - ACS Publications
Silk–elastin-like protein polymers (SELPs), consisting of the repeating units of silk and
elastin blocks, combine a set of outstanding physical and biological properties of silk and …

Silk-elastinlike protein-based hydrogels for drug delivery and embolization

E Griswold, J Cappello, H Ghandehari - Advanced Drug Delivery Reviews, 2022 - Elsevier
Abstract Silk-Elastinlike Protein-Based Polymers (SELPs) can form thermoresponsive
hydrogels that allow for the generation of in-situ drug delivery matrices. They are produced …

Silk-elastin-like protein biomaterials for the controlled delivery of therapeutics

W Huang, A Rollett, DL Kaplan - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Genetically engineered biomaterials are useful for controlled delivery owing to
their rational design, tunable structure–function, biocompatibility, degradability and target …

Challenges and opportunities of silk protein hydrogels in biomedical applications

J Liu, X Ge, L Liu, W Xu, R Shao - Materials Advances, 2022 - pubs.rsc.org
In the context of this era of complementary interdisciplinary advances, the design and
preparation of hydrogel materials has been a hot avenue of research for a variety of …

Fibrous scaffolds from elastin-based materials

JC Rodriguez-Cabello, I Gonzalez De Torre… - … in Bioengineering and …, 2021 - frontiersin.org
Current cutting-edge strategies in biomaterials science are focused on mimicking the design
of natural systems which, over millions of years, have evolved to exhibit extraordinary …

Tuning chemical and physical cross-links in silk electrogels for morphological analysis and mechanical reinforcement

Y Lin, X Xia, K Shang, R Elia, W Huang… - …, 2013 - ACS Publications
Electrochemically controlled, reversible assembly of biopolymers into hydrogel structures is
a promising technique for on-demand cell or drug encapsulation and release systems. An …