Zebrafish patient avatars in cancer biology and precision cancer therapy
In precision oncology, two major strategies are being pursued for predicting clinically
relevant tumour behaviours, such as treatment response and emergence of drug resistance …
relevant tumour behaviours, such as treatment response and emergence of drug resistance …
The resolution of inflammation: Principles and challenges
SE Headland, LV Norling - Seminars in immunology, 2015 - Elsevier
The concept that chemokines, cytokines and pro-inflammatory mediators act in a co-
ordinated fashion to drive the initiation of the inflammatory reaction is well understood. The …
ordinated fashion to drive the initiation of the inflammatory reaction is well understood. The …
A high-resolution mRNA expression time course of embryonic development in zebrafish
We have produced an mRNA expression time course of zebrafish development across 18
time points from 1 cell to 5 days post-fertilisation sampling individual and pools of embryos …
time points from 1 cell to 5 days post-fertilisation sampling individual and pools of embryos …
Zebrafish regulatory T cells mediate organ-specific regenerative programs
SP Hui, DZ Sheng, K Sugimoto, A Gonzalez-Rajal… - Developmental cell, 2017 - cell.com
The attenuation of ancestral pro-regenerative pathways may explain why humans do not
efficiently regenerate damaged organs. Vertebrate lineages that exhibit robust regeneration …
efficiently regenerate damaged organs. Vertebrate lineages that exhibit robust regeneration …
Advances in research of fish immune-relevant genes: a comparative overview of innate and adaptive immunity in teleosts
Fish is considered to be an important model in comparative immunology studies because it
is a representative population of lower vertebrates serving as an essential link to early …
is a representative population of lower vertebrates serving as an essential link to early …
[HTML][HTML] The zebrafish as a model to study intestinal inflammation
S Brugman - Developmental & Comparative Immunology, 2016 - Elsevier
Starting out as a model for developmental biology, during the last decade, zebrafish have
also gained the attention of the immunologists and oncologists. Due to its small size, high …
also gained the attention of the immunologists and oncologists. Due to its small size, high …
Immune system and immune responses in fish and their role in comparative immunity study: a model for higher organisms
The basal position of fish in vertebrate phylogeny makes them very attractive for genomic
and functional comparative immunity studies. Adaptive immunity arose early in vertebrate …
and functional comparative immunity studies. Adaptive immunity arose early in vertebrate …
Toxicity of silver nanoparticles in zebrafish models
This study was initiated to enhance our insight on the health and environmental impact of
silver nanoparticles (Ag-np). Using starch and bovine serum albumin (BSA) as capping …
silver nanoparticles (Ag-np). Using starch and bovine serum albumin (BSA) as capping …
Identification of polarized macrophage subsets in zebrafish
M Nguyen-Chi, B Laplace-Builhe, J Travnickova… - Elife, 2015 - elifesciences.org
While the mammalian macrophage phenotypes have been intensively studied in vitro, the
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …
A transgenic zebrafish model of neutrophilic inflammation
We have established an in vivo model for genetic analysis of the inflammatory response by
generating a transgenic zebrafish line that expresses GFP under the neutrophil-specific …
generating a transgenic zebrafish line that expresses GFP under the neutrophil-specific …