Inflammation response of epithelial mucosa to chemo-radiotherapy cytotoxic effects leads to
mucositis, a painful side effect of antineoplastic treatments. About 40% of the patients treated …

The purpose of this study is to explore the possibilities for the application of laser therapy in
medicine and dentistry by analyzing lasers' underlying mechanism of action on different …

Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …

Cancer is a multifactorial pathology and it represents the second leading cause of death
worldwide. In the recent years, numerous studies highlighted the dual role of the gut …

The gut microbiome (GM) has been implicated in a vast number of human pathologies and
has become a focus of oncology research over the past 5 years. The normal gut microbiota …

Since its clinical introduction in 1998, the topoisomerase I inhibitor irinotecan has been
widely used in the treatment of solid tumors, including colorectal, pancreatic, and lung …

Disclaimer This article is based on recommendations from the 12th WALT Congress, Nice,
October 3-6, 2018, and a follow-up review of the existing data and the clinical observations …

Patients undergoing radiation therapy for the head and neck are susceptible to a significant
and often abrupt deterioration in their oral health. The oral morbidities of radiation therapy …

Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

Despite the enthusiasm surrounding novel targeted agents and immunotherapies,
chemotherapy remains the mainstay treatment for most human malignancies, either alone or …