Hyperpolarized 129Xe MRI of the human lung
JP Mugler III, TA Altes - Journal of Magnetic Resonance …, 2013 - Wiley Online Library
By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
Feasibility, tolerability and safety of pediatric hyperpolarized 129Xe magnetic resonance imaging in healthy volunteers and children with cystic fibrosis
Abstract Background Hyperpolarized 129 Xe is a promising contrast agent for MRI of
pediatric lung function, but its safety and tolerability in children have not been rigorously …
pediatric lung function, but its safety and tolerability in children have not been rigorously …
Using hyperpolarized 129Xe MRI to quantify the pulmonary ventilation distribution
Rationale and Objectives Ventilation heterogeneity is impossible to detect with spirometry.
Alternatively, pulmonary ventilation can be imaged three-dimensionally using inhaled 129 …
Alternatively, pulmonary ventilation can be imaged three-dimensionally using inhaled 129 …
Quantification of regional fractional ventilation in human subjects by measurement of hyperpolarized 3He washout with 2D and 3D MRI
FC Horn, MH Deppe, H Marshall… - Journal of applied …, 2014 - journals.physiology.org
Multiple-breath washout hyperpolarized 3He MRI was used to calculate regional parametric
images of fractional ventilation (r) as the ratio of fresh gas entering a volume unit to the total …
images of fractional ventilation (r) as the ratio of fresh gas entering a volume unit to the total …
Hyperpolarized and inert gas MRI: the future
Magnetic resonance imaging (MRI) is a potentially ideal imaging modality for noninvasive,
nonionizing, and longitudinal assessment of disease. Hyperpolarized (HP) agents have …
nonionizing, and longitudinal assessment of disease. Hyperpolarized (HP) agents have …
Regional Fractional Ventilation by Using Multibreath Wash-in 3He MR Imaging
H Hamedani, JT Clapp, SJ Kadlecek, K Emami, M Ishii… - Radiology, 2016 - pubs.rsna.org
Purpose To assess the feasibility and optimize the accuracy of the multibreath wash-in
hyperpolarized helium 3 (3He) approach to ventilation measurement by using magnetic …
hyperpolarized helium 3 (3He) approach to ventilation measurement by using magnetic …
In vivo regional ventilation mapping using fluorinated gas MRI with an x‐centric FGRE method
Purpose Inert fluorinated gas lung MRI is a new and promising alternative to hyperpolarized
gas lung MRI; it is less expensive and does not require expensive isotopes/polarizers. The …
gas lung MRI; it is less expensive and does not require expensive isotopes/polarizers. The …
[HTML][HTML] Functional lung imaging using novel and emerging MRI techniques
CT Foo, D Langton, BR Thompson, F Thien - Frontiers in Medicine, 2023 - frontiersin.org
Respiratory diseases are leading causes of death and disability in the world. While early
diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools …
diagnosis is key, this has proven difficult due to the lack of sensitive and non-invasive tools …
[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches
SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …