RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

RNA binding proteins that act at the post-transcriptional level display a richness of
mechanisms to modulate the transcriptional output and respond to changing cellular …

Background Gliomas are the most common malignant primary brain tumours with a highly
immunosuppressive tumour microenvironment (TME) and poor prognosis. Circular RNAs …

Background Gastric cancer (GC) is one of the most pernicious tumors that seriously harm
human healthcare. GC metastasis is one of the prime cause of failed cancer treatment, but …

Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms
governing metastatic spread may uncover important tumor biology and/or yield promising …

RNA-binding proteins (RBPs) are essential modulators of transcription and translation
frequently dysregulated in cancer. We systematically interrogated RBP dependencies in …

Abstract N6-methyladenosine (m6A) is the most abundant posttranscriptional modification of
mRNA in eukaryotes. Recent evidence suggests that dysregulated m6A-associated proteins …

Large-scale transcriptome sequencing efforts have vastly expanded the catalog of long non-
coding RNAs (lncRNAs) with varying evolutionary conservation, lineage expression, and …

ABSTRACT RNA-binding proteins (RBPs) are key players in cellular physiology through
posttranscriptional regulation of the expression of target RNA transcripts. By modulating the …

RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …