Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
MicroRNAs in pulmonary arterial hypertension
G Zhou, T Chen, JU Raj - American journal of respiratory cell and …, 2015 - atsjournals.org
Pulmonary arterial hypertension (PAH) is a devastating disease without effective treatment.
Despite decades of research and the development of novel treatments, PAH remains a fatal …
Despite decades of research and the development of novel treatments, PAH remains a fatal …
Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer
Purpose MicroRNAs (miRNAs) play an essential role in breast malignant tumor
development and progression. The development of clinically validated biomarkers for …
development and progression. The development of clinically validated biomarkers for …
MiRGator v3. 0: a microRNA portal for deep sequencing, expression profiling and mRNA targeting
Biogenesis and molecular function are two key subjects in the field of microRNA (miRNA)
research. Deep sequencing has become the principal technique in cataloging of miRNA …
research. Deep sequencing has become the principal technique in cataloging of miRNA …
Population differences in microRNA expression and biological implications
Population differences observed for complex traits may be attributed to the combined effect
of socioeconomic, environmental, genetic and epigenetic factors. To better understand …
of socioeconomic, environmental, genetic and epigenetic factors. To better understand …
Improving bioinformatics prediction of microRNA targets by ranks aggregation
microRNAs are noncoding RNAs which downregulate a large number of target mRNAs and
modulate cell activity. Despite continued progress, bioinformatics prediction of microRNA …
modulate cell activity. Despite continued progress, bioinformatics prediction of microRNA …
Biomarker MicroRNAs for diagnosis, prognosis and treatment of hepatocellular carcinoma: a functional survey and comparison
Hepatocellular Carcinoma (HCC) is one of the most common malignant tumors with high
incidence and mortality rate. Precision and effective biomarkers are therefore urgently …
incidence and mortality rate. Precision and effective biomarkers are therefore urgently …
Identification of candidate miRNA biomarkers from miRNA regulatory network with application to prostate cancer
Background MicroRNAs (miRNAs) are a class of non-coding regulatory RNAs approximately
22 nucleotides in length that play a role in a wide range of biological processes. Abnormal …
22 nucleotides in length that play a role in a wide range of biological processes. Abnormal …
Joint analysis of miRNA and mRNA expression data
A Muniategui, J Pey, FJ Planes… - Briefings in …, 2013 - academic.oup.com
Abstract miRNAs are small RNA molecules (′ 22 nt) that interact with their target mRNAs
inhibiting translation or/and cleavaging the target mRNA. This interaction is guided by …
inhibiting translation or/and cleavaging the target mRNA. This interaction is guided by …
MicroRNA regulation of molecular networks mapped by global microRNA, mRNA, and protein expression in activated T lymphocytes
MicroRNAs (miRNAs) regulate specific immune mechanisms, but their genome-wide
regulation of T lymphocyte activation is largely unknown. We performed a multidimensional …
regulation of T lymphocyte activation is largely unknown. We performed a multidimensional …