The availability of engineered biological tissues holds great potential for both clinical
applications and basic research in a life science laboratory. A prototype standalone …

Tissue-engineered bone tissue grafts are a promising alternative to the more conventional
use of natural donor bone grafts. However, choosing an appropriate biomaterial/scaffold to …

Conventional 2D cell culture, a traditional tool in pre-clinical studies, can hardly be regarded
as a representation of a natural cell microenvironment. In this respect, it might result in …

Cell‐based in vitro biological models traditionally use monolayer cell cultures grown over
plastic surfaces bathing in static media. Higher fidelity to a natural biological tissue is …

Dynamic culture protocols have recently emerged as part of (bone) tissue engineering
strategies due to their ability to represent a more physiological cell environment in vitro …

3D printing has opened exciting new opportunities for the in vitro fabrication of
biocompatible hybrid pseudo-tissues. Technologies based on additive manufacturing herald …

In this work, a 3D environment obtained using fibrin scaffold and two cell populations, such
as bone marrow-derived mesenchymal stem cells (BM-MSCs), and primary skeletal muscle …

Computational simulations are becoming increasingly relevant in biomedical research,
providing strategies to reproduce experimental results, improve the resolution of in-vitro …

Objective. 3D cell cultures are becoming a fundamental resource for in-vitro studies, as they
mimic more closely in-vivo behavior. The analysis of these constructs, however, generally …

Monitoring bone tissue engineered (TEed) constructs during their maturation is important to
ensure the quality of applied protocols. Several destructive, mainly histochemical, methods …