Neuroimaging of Parkinson's disease: Expanding views

CP Weingarten, MH Sundman, P Hickey… - … & Biobehavioral Reviews, 2015 - Elsevier
Advances in molecular and structural and functional neuroimaging are rapidly expanding
the complexity of neurobiological understanding of Parkinson's disease (PD). This review …

Psychosis in Parkinson's disease: epidemiology, pathophysiology, and management

A Chang, SH Fox - Drugs, 2016 - Springer
Psychotic symptoms are common in Parkinson's disease (PD) and are associated with
poorer quality of life and increased caregiver burden. PD psychosis is correlated with …

[HTML][HTML] Classification of PPMI MRI scans with voxel-based morphometry and machine learning to assist in the diagnosis of Parkinson's disease

G Solana-Lavalle, R Rosas-Romero - Computer Methods and Programs in …, 2021 - Elsevier
Background and objectives: Qualitative and quantitative analyses of Magnetic Resonance
Imaging (MRI) scans are carried out to study and understand Parkinson's Disease, the …

Network connectivity determines cortical thinning in early Parkinson's disease progression

Y Yau, Y Zeighami, TE Baker, K Larcher… - Nature …, 2018 - nature.com
Here we test the hypothesis that the neurodegenerative process in Parkinson's disease (PD)
moves stereotypically along neural networks, possibly reflecting the spread of toxic alpha …

Gray matter, white matter and cerebrospinal fluid abnormalities in Parkinson's disease: A voxel-based morphometry study

CO Nyatega, L Qiang, MJ Adamu… - Frontiers in Psychiatry, 2022 - frontiersin.org
Background Parkinson's disease (PD) is a chronic neurodegenerative disorder
characterized by bradykinesia, tremor, and rigidity among other symptoms. With a 70 …

[HTML][HTML] Dopamine and the brainstem locomotor networks: from lamprey to human

D Ryczko, R Dubuc - Frontiers in neuroscience, 2017 - frontiersin.org
In vertebrates, dopamine neurons are classically known to modulate locomotion via their
ascending projections to the basal ganglia that project to brainstem locomotor networks. An …

Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity

C Ran, Y Yang, C Ye, H Lv, T Ma - Human brain mapping, 2022 - Wiley Online Library
Neuroimaging‐driven brain age estimation has become popular in measuring brain aging
and identifying neurodegenerations. However, the single estimated brain age (gap) …

Shared molecular genetic factors influence subcortical brain morphometry and Parkinson's disease risk

LM García-Marín, P Reyes-Pérez, S Diaz-Torres… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is a late-onset and genetically complex neurodegenerative
disorder. Here we sought to identify genes and molecular pathways underlying the …

[HTML][HTML] Noradrenergic dysfunction in Alzheimer's and Parkinson's diseases—An overview of imaging studies

AC Peterson, CSR Li - Frontiers in Aging Neuroscience, 2018 - frontiersin.org
Noradrenergic dysfunction contributes to cognitive impairment in Alzheimer's Disease (AD)
and Parkinson's Disease (PD). Conventional therapeutic strategies seek to enhance …

The pattern of gray matter atrophy in Parkinson's disease differs in cortical and subcortical regions

MM Lewis, G Du, EY Lee, Z Nasralah, NW Sterling… - Journal of …, 2016 - Springer
Cortical and subcortical gray matter (GM) atrophy may progress differently during the course
of Parkinson's disease (PD). We delineated and compared the longitudinal pattern of these …