Intracytoplasmic sperm injection for male infertility and consequences for offspring

SC Esteves, M Roque, G Bedoschi, T Haahr… - Nature Reviews …, 2018 - nature.com
Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Role of genetics and epigenetics in male infertility

S Gunes, SC Esteves - Andrologia, 2021 - Wiley Online Library
Male infertility is a complex condition with a strong genetic and epigenetic background. This
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …

[HTML][HTML] Reproductive outcomes of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with high levels of DNA fragmentation in semen …

SC Esteves, M Roque, CK Bradley, N Garrido - Fertility and sterility, 2017 - Elsevier
Objective To compare sperm DNA fragmentation (SDF) levels between testicular and
ejaculated sperm and to evaluate outcomes of intracytoplasmic sperm injection (ICSI) with …

Microdissection testicular sperm extraction (micro-TESE) in men with infertility due to nonobstructive azoospermia: summary of current literature

APP Achermann, TA Pereira, SC Esteves - International Urology and …, 2021 - Springer
Purpose Nonobstructive azoospermia (NOA) is associated with intrinsic testicular defects
that severely impair sperm production. Although NOA invariably leads to infertility, focal …

Clinical application of aromatase inhibitors to treat male infertility

C Yang, P Li, Z Li - Human Reproduction Update, 2022 - academic.oup.com
BACKGROUND Infertility affects 15% of men and contributes to nearly half of all cases of
infertility. Infertile men usually have impaired spermatogenesis, presenting as azoospermia …

Outcome of varicocele repair in men with nonobstructive azoospermia: systematic review and meta-analysis

SC Esteves, R Miyaoka, M Roque… - Asian Journal of …, 2016 - journals.lww.com
The objective of this systemic review was to evaluate the benefit of repairing clinical
varicocele in infertile men with nonobstructive azoospermia (NOA). The surgically obtained …

Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia

C Xie, W Wang, C Tu, L Meng, G Lu… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Meiosis is an essential stage in the life cycle of sexually reproducing
species, underlying formation of haploid gametes and serving as the basis of genetic …

Differential diagnosis of azoospermia in men with infertility

DL Andrade, MC Viana, SC Esteves - Journal of clinical medicine, 2021 - mdpi.com
The differential diagnosis between obstructive and nonobstructive azoospermia is the first
step in the clinical management of azoospermic patients with infertility. It includes a detailed …

[HTML][HTML] Comparison of reproductive outcome in oligozoospermic men with high sperm DNA fragmentation undergoing intracytoplasmic sperm injection with …

SC Esteves, F Sánchez-Martín, P Sánchez-Martín… - Fertility and sterility, 2015 - Elsevier
Objective To investigate the effectiveness of intracytoplasmic sperm injection (ICSI) using
testicular sperm as a strategy to overcome infertility in men with high sperm DNA …

[HTML][HTML] Experimental methods to preserve male fertility and treat male factor infertility

K Gassei, KE Orwig - Fertility and sterility, 2016 - Elsevier
Infertility is a prevalent condition that has insidious impacts on the infertile individuals, their
families, and society, which extend far beyond the inability to have a biological child …