Marginal zone B cells in lymphocyte activation and regulation
T Lopes-Carvalho, J Foote, JF Kearney - Current opinion in immunology, 2005 - Elsevier
Marginal zone (MZ) B cells, together with other strategically located innate cells, constitute
the first line of defense against blood-borne microorganisms, viruses and toxins in the …
the first line of defense against blood-borne microorganisms, viruses and toxins in the …
Complement-mediated activation of the adaptive immune responses: role of C3d in linking the innate and adaptive immunity
FR Toapanta, TM Ross - Immunologic research, 2006 - Springer
C3d is the final degradation product of the third component of complement (C3). When
conjugated to an antigen, C3d enhances immune responses to the fused antigen. Therefore …
conjugated to an antigen, C3d enhances immune responses to the fused antigen. Therefore …
[HTML][HTML] Identification and characterization of the C3 binding domain of the Staphylococcus aureus extracellular fibrinogen-binding protein (Efb)
The secreted Staphylococcus aureus extracellular fibrinogen-binding protein (Efb) is a
virulence factor that binds to both the complement component C3b and fibrinogen. Our …
virulence factor that binds to both the complement component C3b and fibrinogen. Our …
[HTML][HTML] Phagocytosis by human neutrophils is stimulated by a unique fungal cell wall component
I Rubin-Bejerano, C Abeijon, P Magnelli, P Grisafi… - Cell host & …, 2007 - cell.com
Innate immunity depends upon recognition of surface features common to broad groups of
pathogens. The glucose polymer β-glucan has been implicated in fungal immune …
pathogens. The glucose polymer β-glucan has been implicated in fungal immune …
Size-dependent neutralizing activity of gold nanoparticle-based subunit vaccine against dengue virus
Dengue results in substantial human morbidity and significant socio-economic impacts, but
a specific dengue therapeutic is not available. The currently available dengue vaccine has …
a specific dengue therapeutic is not available. The currently available dengue vaccine has …
Regulation of B lymphocyte activation by complement C3 and the B cell coreceptor complex
RC Rickert - Current opinion in immunology, 2005 - Elsevier
Complement is an essential innate immune mechanism that recognizes and eradicates
microbes and associated toxins. In addition, complement receptors (CD21 and CD35) on B …
microbes and associated toxins. In addition, complement receptors (CD21 and CD35) on B …
Complement-mediated 'bystander'damage initiates host NLRP3 inflammasome activation
R Suresh, P Chandrasekaran… - Journal of cell …, 2016 - journals.biologists.com
Complement activation has long been associated with inflammation, primarily due to the
elaboration of the complement anaphylotoxins C5a and C3a. In this work, we demonstrate …
elaboration of the complement anaphylotoxins C5a and C3a. In this work, we demonstrate …
[HTML][HTML] Plasmid-encoded toxin of Escherichia coli cleaves complement system proteins and inhibits complement-mediated lysis in vitro
GB Correa, CA Freire, M Dibo… - Frontiers in Cellular …, 2024 - frontiersin.org
Plasmid-encoded toxin (Pet) is an autotransporter protein of the serine protease
autotransporters of Enterobacteriaceae (SPATE) family, important in the pathogenicity of …
autotransporters of Enterobacteriaceae (SPATE) family, important in the pathogenicity of …
The CD19-CD21 signal transduction complex of B lymphocytes regulates the balance between health and autoimmune disease: systemic sclerosis as a model system
TF Tedder, JC Poe, M Fujimoto, KM Haas… - B Cell Trophic Factors …, 2005 - karger.com
Cell-surface CD19 functions as a general rheostat for defining intrinsic and antigen receptor-
induced signaling thresholds critical for clonal expansion of the B cell pool and humoral …
induced signaling thresholds critical for clonal expansion of the B cell pool and humoral …
Role of the CD19 and CD21/35 receptor complex in innate immunity, host defense and autoimmunity
KM Haas, TF Tedder - Mechanisms of Lymphocyte Activation and Immune …, 2005 - Springer
Humoral immune responses to foreign and self-antigens must be tightly regulated to
facilitate protective immunity to pathogens while avoiding autoimmune responses. The …
facilitate protective immunity to pathogens while avoiding autoimmune responses. The …