Targeting tumor microenvironment by metal peroxide nanoparticles in cancer therapy

SN Mbugua - Bioinorganic Chemistry and Applications, 2022 - Wiley Online Library
Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …

Applications of single-site iron nanozymes in biomedicine

J Han, J Guan - Coordination Chemistry Reviews, 2023 - Elsevier
With the vigorous development of nanozymes in recent years, single-site nanozymes (SSNs)
with maximum atomic utilization of 100% have become a popular research frontier in various …

Reticular Chemistry‐Enabled Sonodynamic Activity of Covalent Organic Frameworks for Nanodynamic Cancer Therapy

Y Duan, Y Yu, P Liu, Y Gao, X Dai, L Zhang… - Angewandte …, 2023 - Wiley Online Library
The development of covalent organic framework (COF) sonosensitizers with intrinsic
sonodynamic effects is highly desirable. However, such COFs are generally constructed …

Hydrogen sulfide gas amplified ROS cascade: FeS@ GOx hybrid nanozyme designed for boosting tumor chemodynamic immunotherapy

W Sun, C Zhu, J Song, SC Ji, BP Jiang… - Advanced …, 2023 - Wiley Online Library
Chemodynamic immunotherapy that utilizes catalysts to produce reactive oxygen species
(ROS) for killing tumor cells and arousing antitumor immunity has received considerable …

Porphyrin-based covalent organic framework with self-accelerated M− N4 bimetallic active sites for enhanced electrochemical detection of trace hydrogen peroxide

Y Bai, W Gao, Q Wang, B Yu, J Wei, C Gao… - Sensors and Actuators B …, 2023 - Elsevier
The ultrasensitive detection of trace hydrogen peroxide (H 2 O 2) has been a fascinating
research topic owing to its significant application in environmental monitoring, food safety …

Mn-single-atom nano-multizyme enabled NIR-II photoacoustically monitored, photothermally enhanced ROS storm for combined cancer therapy

X Wang, X Ren, J Yang, Z Zhao, X Zhang… - Biomaterials …, 2023 - spj.science.org
Rationale To realize imaging-guided multi-modality cancer therapy with minimal side effects
remains highly challenging. Methods We devised a bioinspired hollow nitrogen-doped …

Exogenous application of selenium on sunflower (Helianthus annuus L.) to enhance drought stress tolerance by morpho-physiological and biochemical adaptations

M Ameen, MA Zia, HF Najeeb Alawadi… - Frontiers in Plant …, 2024 - frontiersin.org
Drought stress poses a significant obstacle to agricultural productivity, particularly in the
case of oilseed crops such as sunflower (Helianthus annuus L.). Selenium (Se) is a …

Bioengineered nanogenerator with sustainable reactive oxygen species storm for self-reinforcing sono-chemodynamic oncotherapy

D Shi, F Wu, L Huang, Y Li, S Ke, J Li, Z Hou… - Journal of Colloid and …, 2023 - Elsevier
Oxidative stress-based antitumor modalities derived from reactive oxygen species (ROS)
storms have attracted increasing attention. Nevertheless, low delivery efficiency, poor …

N-Rich and Sulfur-Doped Nano Hollow Carbons with High Oxidase-like Activity Prepared Using a Green Template of CaCO3 for Bacteriostasis

L Liu, J Deng, Y Wang, X He, H He, X Chen, D Liao… - Langmuir, 2023 - ACS Publications
Nanozymes, enzyme-mimicking nanomaterials, have attracted increasing attention due to
their low cost, high stability, and catalytic ability compared with natural enzymes. However …

Achieving Complete Tumor Clearance: A Minimalist Manganese Hydrogel for Magnetic Resonance Imaging‐Guided Synergetic Microwave Ablation and …

Y Zhou, G Shu, Y Luo, F Wang, X Jing… - Advanced …, 2024 - Wiley Online Library
The combination of microwave ablation (MWA) and chemodynamic therapy (CDT) presents
a promising strategy for complete eradication of residual tumor after MWA. However, it …