New advances in metabolic syndrome, from prevention to treatment: the role of diet and food

D Ambroselli, F Masciulli, E Romano, G Catanzaro… - Nutrients, 2023 - mdpi.com
The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

The role of polyphenol (flavonoids) compounds in the treatment of cancer cells

A Hazafa, KU Rehman, N Jahan, Z Jabeen - Nutrition and cancer, 2020 - Taylor & Francis
Cancer remains a second leading cause of deaths and major public health problem. It
occurs due to extensive DNA damage caused by ultraviolet radiations, ionizing radiations …

Flavones: from biosynthesis to health benefits

N Jiang, AI Doseff, E Grotewold - Plants, 2016 - mdpi.com
Flavones correspond to a flavonoid subgroup that is widely distributed in the plants, and
which can be synthesized by different pathways, depending on whether they contain C-or O …

Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages

X Zhang, G Wang, EC Gurley, H Zhou - PloS one, 2014 - journals.plos.org
Background Apigenin is a non-toxic natural flavonoid that is abundantly present in common
fruits and vegetables. It has been reported that apigenin has various beneficial health effects …

The potential role of flavonoids in ameliorating diabetic cardiomyopathy via alleviation of cardiac oxidative stress, inflammation and apoptosis

FF Jubaidi, S Zainalabidin, IS Taib, ZA Hamid… - International journal of …, 2021 - mdpi.com
Diabetic cardiomyopathy is one of the major mortality risk factors among diabetic patients
worldwide. It has been established that most of the cardiac structural and functional …

Plant flavonoids in cancer chemoprevention: role in genome stability

VC George, G Dellaire, HPV Rupasinghe - The Journal of nutritional …, 2017 - Elsevier
Carcinogenesis is a multistage process that involves a series of events comprising of
genetic and epigenetic changes leading to the initiation, promotion and progression of …

Complementary effects of cereal and pulse polyphenols and dietary fiber on chronic inflammation and gut health

JM Awika, DJ Rose, S Simsek - Food & function, 2018 - pubs.rsc.org
Cereal grains and grain pulses are primary staples often consumed together, and contribute
a major portion of daily human calorie and protein intake globally. Protective effects of …

Role of flavonoids in management of inflammatory disorders

R Shukla, V Pandey, GP Vadnere, S Lodhi - Bioactive food as dietary …, 2019 - Elsevier
Flavonoids are a wide category of polyphenolic compounds that have a major role in the
treatment of various inflammatory diseases, including arthritis, gastritis, nephritis, hepatitis …

Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells

KM Perrott, CD Wiley, PY Desprez, J Campisi - Geroscience, 2017 - Springer
Abstract Apigenin (4′, 5, 7,-trihydroxyflavone) is a flavonoid found in certain herbs, fruits,
and vegetables. Apigenin can attenuate inflammation, which is associated with many …

Oxidative stress in cardiovascular disease

G Csányi, FJ Miller Jr - International journal of molecular sciences, 2014 - mdpi.com
In the special issue “Oxidative Stress in Cardiovascular Disease” authors were invited to
submit papers that investigate key questions in the field of cardiovascular free radical …