Osteoporosis is a common metabolic bone disease, influenced by genetic and
environmental factors, that increases bone fragility and fracture risk and, therefore, has a …

While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …

Long non-coding RNAs (lncRNAs) have gained great attention as epigenetic regulators of
gene expression in many tissues. Increasing evidence indicates that lncRNAs, together with …

For the last four decades, we have known that noncoding RNAs maintain critical
housekeeping functions such as transcription, RNA processing, and translation. However, in …

Rationale: Emerging evidence indicates that the growth of blood vessels and osteogenesis
is tightly coordinated during bone development. However, the molecular regulators of …

Background: Calcific aortic valve disease is characterized by an abnormal mineralization of
the aortic valve. Osteogenic activity in the aortic valve is under the control of NOTCH1, which …

Phenolic compounds are natural phytochemicals that have recently reported numerous
health benefits. Resveratrol, curcumin, and quercetin have recently received the most …