Lipid metabolism reprogramming in cardiac fibrosis

LC Lin, ZY Liu, JJ Yang, JY Zhao, H Tao - Trends in Endocrinology & …, 2024 - cell.com
Cardiac fibrosis is a critical pathophysiological process that occurs with diverse types of
cardiac injury. Lipids are the most important bioenergy substrates for maintaining optimal …

Matrix metalloproteinases in Cardioembolic stroke: from background to complications

A Wysocka, J Szczygielski, M Kopańska… - International Journal of …, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are endopeptidases participating in physiological
processes of the brain, maintaining the blood–brain barrier integrity and playing a critical …

Characterization of a robust mouse model of heart failure with preserved ejection fraction

D Matsiukevich, A Kovacs, T Li… - American Journal …, 2023 - journals.physiology.org
Heart failure (HF) is a leading cause of morbidity and mortality particularly in older adults
and patients with multiple metabolic comorbidities. Heart failure with preserved ejection …

Serum myostatin level is associated with myocardial scar burden by SPECT myocardial perfusion imaging

JY Chiang, L Lin, CC Wu, JJ Hwang, WS Yang… - Clinica Chimica …, 2022 - Elsevier
Background Myostatin is a negative regulator of skeletal muscle and myocardial mass. The
relationship between myocardial ischemia and scar burden and levels of myostatin has not …

Role of Galectin in Cardiovascular Conditions including Cirrhotic Cardiomyopathy

H Liu, SY Hwang, SS Lee - Pharmaceuticals, 2023 - mdpi.com
Abnormal cardiac function in the setting of cirrhosis and in the absence of a primary cardiac
disease is known as cirrhotic cardiomyopathy. The pathogenesis of cirrhotic cardiomyopathy …

New biomarkers and their potential role in heart failure treatment optimisation—An African perspective

M Badianyama, D Mpanya, U Adamu… - Journal of …, 2022 - mdpi.com
Heart failure is a clinical syndrome resulting from various cardiovascular diseases of
different aetiologies and pathophysiology. These varying pathologies involve several …

The extent of postpartum cardiac reverse remodeling is reflected in urine proteome

AF Ferreira, F Trindade, MJ Azevedo, J Morais… - Scientific Reports, 2024 - nature.com
The association of postpartum cardiac reverse remodeling (RR) with urinary proteome,
particularly in pregnant women with cardiovascular (CV) risk factors who show long-term …

PTN secreted by cardiac fibroblasts promotes myocardial fibrosis and inflammation of pressure overload-induced hypertrophic cardiomyopathy through the PTN …

K Sheng, Y Ran, X Feng, Y Wang, S Zhou, Y Guan… - Life Sciences, 2025 - Elsevier
Aims Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left ventricular
hypertrophy (LVH) with key pathologic processes including myocardial necrosis, fibrosis …

Salvianolic Acid B Inhibits Myocardial Fibrosis during Diabetic Cardiomyopathy via Suppressing TRPC6 and TGF‐β/Smad3 Pathway

P Lu, M Zhang, Z Chen, QY Xu, M Liu… - Journal of Food …, 2024 - Wiley Online Library
Salvianolic acid B (Sal B), the main water‐soluble polyphenolic constituent of Danshen, is
noted for its anti‐inflammatory, antioxidant, and antiapoptotic properties, particularly in …

Harnessing the lymphatic system

B Ponikowska, M Fudim, G Iwanek, R Zymliński… - Heart Failure …, 2024 - Springer
Heart failure (HF) is a growing concern, with significant implications for mortality, morbidity,
and economic sustainability. Traditionally viewed primarily as a hemodynamic disorder …