Advancements and challenges in antifungal therapeutic development
Over recent decades, the global burden of fungal disease has expanded dramatically. It is
estimated that fungal disease kills approximately 1.5 million individuals annually; however …
estimated that fungal disease kills approximately 1.5 million individuals annually; however …
[HTML][HTML] Modulatory immune responses in fungal infection associated with organ transplant-advancements, management, and challenges
A Elalouf, H Elalouf, A Rosenfeld - Frontiers in Immunology, 2023 - frontiersin.org
Organ transplantation stands as a pivotal achievement in modern medicine, offering hope to
individuals with end-stage organ diseases. Advancements in immunology led to improved …
individuals with end-stage organ diseases. Advancements in immunology led to improved …
[HTML][HTML] Advancing Vaccine Strategies against Candida Infections: Exploring New Frontiers
Candida albicans, along with several non-albicans Candida species, comprise a prominent
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …
[HTML][HTML] New Immunological Markers in Chromoblastomycosis—The Importance of PD-1 and PD-L1 Molecules in Human Infection
IN Cavallone, W Belda Jr, CHC de Carvalho… - Journal of Fungi, 2023 - mdpi.com
The pathogenesis of chromoblastomycosis (CBM) is associated with Th2 and/or T regulatory
immune responses, while resistance is associated with a Th1 response. However, even in …
immune responses, while resistance is associated with a Th1 response. However, even in …
[HTML][HTML] Global Transcriptomic Profiling of Innate and Adaptive Immunity During Aspergillus flavus Endophthalmitis in a Murine Model
A Khapuinamai, D Rudraprasad… - … & visual science, 2024 - iovs.arvojournals.org
Purpose: Fungal endophthalmitis is characterized by chronic inflammation leading to the
partial or complete vision loss. Herein, we analyzed the transcriptomic landscape of …
partial or complete vision loss. Herein, we analyzed the transcriptomic landscape of …
Engineered yeast cells simulating CD19+ cancers to control CAR T cell activation
M Deichmann, G Schiesaro, K Ramanathan… - bioRxiv, 2023 - biorxiv.org
Chimeric antigen receptor (CAR) T cells have become an established form of
immunotherapy and continue to show promising results for the treatment of hematological …
immunotherapy and continue to show promising results for the treatment of hematological …
[PDF][PDF] Advancing Vaccine Strategies against Candida Infections: Exploring New Frontiers. Vaccines 2023, 11, 1658
Candida albicans, along with several non-albicans Candida species, comprise a prominent
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …
fungal pathogen in humans, leading to candidiasis in various organs. The global impact of …
[HTML][HTML] HIV-Associated Histoplasmosis
RC Cernat - 2023 - intechopen.com
Impaired immunity induced by HIV is one of the main causes of disseminated histoplasmosis
in endemic areas, and thus from 1987 WHO and then the CDC classified this condition as an …
in endemic areas, and thus from 1987 WHO and then the CDC classified this condition as an …