Conspectus Oxidative post-translational modifications (OxiPTMs) of cysteine residues are
the molecular foundation of thiol-based redox regulation that modulates physiological …

Fluorescence microscopy has become a critical tool for researchers to understand biological
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …

Silver nanoparticles (AgNPs) are widely used nanomaterials in both commercial and clinical
biomedical applications, due to their antibacterial properties. AgNPs are also being explored …

Mitochondria, colloquially known as “the powerhouse of the cell”, play important roles in
production, but also in processes critical for cellular fate such as cell death, differentiation …

Loss-of-function mutations in parkin is associated with onset of juvenile Parkinson's disease
(PD). Resveratrol is a polyphenolic stilbene with neuroprotective activity. Here, we evaluated …

Background Precisely how silver nanoparticles (AgNPs) kill mammalian cells still is not fully
understood. It is not clear if AgNP-induced damage differs from silver cation (Ag+), nor is it …

Sulfur-based functional groups are found in a broad range of natural products and
therapeutic compounds. The sulfoxide moiety is present in a significant portion of …

Tumor penetration of nanoparticles is crucial in nanomedicine, but the mechanisms of tumor
penetration are poorly understood. This work presents a multidimensional, quantitative …

Sulfenylation (RSH→ RSOH) is a post-translational protein modification associated with
cellular mechanisms for signal transduction and the regulation of reactive oxygen species …

Peroxiredoxins have a long-established cellular function as regulators of redox metabolism
by catalyzing the reduction of peroxides (eg, H2O2, lipid peroxides) with high catalytic …