Activity-based sensing for site-specific proteomic analysis of cysteine oxidation
Y Shi, KS Carroll - Accounts of chemical research, 2019 - ACS Publications
Conspectus Oxidative post-translational modifications (OxiPTMs) of cysteine residues are
the molecular foundation of thiol-based redox regulation that modulates physiological …
the molecular foundation of thiol-based redox regulation that modulates physiological …
Fluorescence microscopy—an outline of hardware, biological handling, and fluorophore considerations
Fluorescence microscopy has become a critical tool for researchers to understand biological
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …
Silver nanoparticles induce mitochondrial protein oxidation in lung cells impacting cell cycle and proliferation
Silver nanoparticles (AgNPs) are widely used nanomaterials in both commercial and clinical
biomedical applications, due to their antibacterial properties. AgNPs are also being explored …
biomedical applications, due to their antibacterial properties. AgNPs are also being explored …
Mitochondrial Targeting of Probes and Therapeutics to the Powerhouse of the Cell
Mitochondria, colloquially known as “the powerhouse of the cell”, play important roles in
production, but also in processes critical for cellular fate such as cell death, differentiation …
production, but also in processes critical for cellular fate such as cell death, differentiation …
An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster
AO Adedara, AD Babalola, F Stephano… - Scientific Reports, 2022 - nature.com
Loss-of-function mutations in parkin is associated with onset of juvenile Parkinson's disease
(PD). Resveratrol is a polyphenolic stilbene with neuroprotective activity. Here, we evaluated …
(PD). Resveratrol is a polyphenolic stilbene with neuroprotective activity. Here, we evaluated …
The mechanism of cell death induced by silver nanoparticles is distinct from silver cations
Background Precisely how silver nanoparticles (AgNPs) kill mammalian cells still is not fully
understood. It is not clear if AgNP-induced damage differs from silver cation (Ag+), nor is it …
understood. It is not clear if AgNP-induced damage differs from silver cation (Ag+), nor is it …
Sulfoxides and disulfides from sulfenic acids: Synthesis and applications
CMA Gangemi, E D'Agostino, MC Aversa, A Barattucci… - Tetrahedron, 2023 - Elsevier
Sulfur-based functional groups are found in a broad range of natural products and
therapeutic compounds. The sulfoxide moiety is present in a significant portion of …
therapeutic compounds. The sulfoxide moiety is present in a significant portion of …
Size‐dependent penetration of nanoparticles in tumor spheroids: a multidimensional and quantitative study of transcellular and paracellular pathways
W Chen, W Wang, Z Xie, F Centurion, B Sun… - Small, 2024 - Wiley Online Library
Tumor penetration of nanoparticles is crucial in nanomedicine, but the mechanisms of tumor
penetration are poorly understood. This work presents a multidimensional, quantitative …
penetration are poorly understood. This work presents a multidimensional, quantitative …
Dual-Reactivity trans-Cyclooctenol Probes for Sulfenylation in Live Cells Enable Temporal Control via Bioorthogonal Quenching
Sulfenylation (RSH→ RSOH) is a post-translational protein modification associated with
cellular mechanisms for signal transduction and the regulation of reactive oxygen species …
cellular mechanisms for signal transduction and the regulation of reactive oxygen species …
Peroxiredoxins in cancer and response to radiation therapies
Peroxiredoxins have a long-established cellular function as regulators of redox metabolism
by catalyzing the reduction of peroxides (eg, H2O2, lipid peroxides) with high catalytic …
by catalyzing the reduction of peroxides (eg, H2O2, lipid peroxides) with high catalytic …