[HTML][HTML] Wound healing: a cellular perspective
Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
spatial and temporal synchronization of a variety of cell types with distinct roles in the …
Acute inflammation in tissue healing
AM Soliman, DR Barreda - International Journal of Molecular Sciences, 2022 - mdpi.com
There are well-established links between acute inflammation and successful tissue repair
across evolution. Innate immune reactions contribute significantly to pathogen clearance …
across evolution. Innate immune reactions contribute significantly to pathogen clearance …
[HTML][HTML] SFRP2/DPP4 and FMO1/LSP1 define major fibroblast populations in human skin
Fibroblasts produce matrix, regulate inflammation, mediate reparative processes, and serve
as pluripotent mesenchymal cells. Analyzing digested normal human skin by single-cell …
as pluripotent mesenchymal cells. Analyzing digested normal human skin by single-cell …
Reengineering the tumor microenvironment to alleviate hypoxia and overcome cancer heterogeneity
JD Martin, D Fukumura… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Solid tumors consist of cancer cells and stromal cells, including resident and transiting
immune cells—all ensconced in an extracellular matrix (ECM)—nourished by blood vessels …
immune cells—all ensconced in an extracellular matrix (ECM)—nourished by blood vessels …
Abnormal RNA stability in amyotrophic lateral sclerosis
EM Tank, C Figueroa-Romero, LM Hinder… - Nature …, 2018 - nature.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share key features,
including accumulation of the RNA-binding protein TDP-43. TDP-43 regulates RNA …
including accumulation of the RNA-binding protein TDP-43. TDP-43 regulates RNA …
Generation of inner ear hair cells by direct lineage conversion of primary somatic cells
L Menendez, T Trecek, S Gopalakrishnan, L Tao… - elife, 2020 - elifesciences.org
The mechanoreceptive sensory hair cells in the inner ear are selectively vulnerable to
numerous genetic and environmental insults. In mammals, hair cells lack regenerative …
numerous genetic and environmental insults. In mammals, hair cells lack regenerative …
Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division
JM Replogle, W Zhou, AE Amaro… - Proceedings of the …, 2020 - National Acad Sciences
Aneuploidy, defined as whole chromosome gains and losses, is associated with poor patient
prognosis in many cancer types. However, the condition causes cellular stress and cell cycle …
prognosis in many cancer types. However, the condition causes cellular stress and cell cycle …
Reprogramming of three-dimensional microenvironments for in vitro hair follicle induction
T Kageyama, A Shimizu, R Anakama, R Nakajima… - Science …, 2022 - science.org
During embryonic development, reciprocal interactions between epidermal and
mesenchymal layers trigger hair follicle morphogenesis. This study revealed that …
mesenchymal layers trigger hair follicle morphogenesis. This study revealed that …
Cell competition during reprogramming gives rise to dominant clones
INTRODUCTION Recent advances in lineage tracking using DNA-based barcoding
technologies have provided new insights into the developmental dynamics of cell …
technologies have provided new insights into the developmental dynamics of cell …
Cytotoxicity and transcriptomic analysis of silver nanoparticles in mouse embryonic fibroblast cells
The rapid development of nanotechnology has led to the use of silver nanoparticles (AgNPs)
in biomedical applications, including antibacterial, antiviral, anti-inflammatory, and …
in biomedical applications, including antibacterial, antiviral, anti-inflammatory, and …