We propose an integrated model of aqueous outflow control that employs a pump-conduit
system in this article. Our model exploits accepted physiologic regulatory mechanisms such …

Elevated intraocular pressure (IOP) is the primary risk factor for blindness in glaucoma. IOP
is determined by many factors including aqueous humour production and aqueous humour …

Primary open angle glaucoma (POAG) features an optic neuropathy, elevated aqueous
humor (AH) TGFβ2, and major risk factors of central corneal thickness (CCT), increasing age …

Recent advances in the medical and surgical management of open-angle glaucoma have
increased the number of treatment options available. Several new intraocular pressure (IOP) …

Aqueous humor (AH) and blood levels of transforming growth factor β (TGFβ) are elevated in
idiopathic primary open angle glaucoma (POAG) representing a disease biomarker of …

Purpose: The purpose of this study was to use HVI to illustrate and quantify effects of TBS on
AO through the episcleral venous system. Design: This is a prospective observational cohort …

Background: Schlemm's canal (SC) targeted procedures constitute a promising therapy for
open angle glaucoma (POAG), safer and less invasive. However, little attention was paid to …

The effect of trabecular meshwork (TM)-targeted minimally invasive glaucoma surgery
(MIGS) on the vasculature assessed using anterior segment (AS)-optical coherence …

A wave of less invasive surgical options that target or bypass the conventional aqueous
outflow system has been incorporated into routine clinical practice to mitigate surgical risks …

The human eye has a unique immune architecture and behavior. While the conjunctiva is
known to have a well-defined lymphatic drainage system, the cornea, sclera, and uveal …