A Tale about Shigella: Evolution, Plasmid, and Virulence

N Haidar-Ahmad, FO Manigat, N Silué, SM Pontier… - Microorganisms, 2023 - mdpi.com
Shigella spp. cause hundreds of millions of intestinal infections each year. They target the
mucosa of the human colon and are an important model of intracellular bacterial …

Recent insights into type-3 secretion system injectisome structure and mechanism of human enteric pathogens

P Chen, MB Goldberg - Current opinion in microbiology, 2023 - Elsevier
Type-3 secretion system injectisomes are multiprotein complexes that translocate bacterial
effector proteins from the cytoplasm of gram-negative bacteria directly into the cytosol of …

Efficient production of immunologically active Shigella invasion plasmid antigens IpaB and IpaH using a cell-free expression system

N Kapoor, E Ndungo, L Pill, G Desalegn… - Applied Microbiology …, 2022 - Springer
Shigella spp. invade the colonic epithelium and cause bacillary dysentery in humans.
Individuals living in areas that lack access to clean water and sanitation are the most …

Characterization of Functional B-Cell Epitopes at the Amino Terminus of Shigella Invasion Plasmid Antigen B (IpaB)

S Li, X Han, I Upadhyay, W Zhang - Applied and environmental …, 2022 - Am Soc Microbiol
Shigella invasion plasmid antigen B (IpaB) plays an important role in causing shigellosis.
While IpaB's protein structure, contribution to disease mechanism, and protective immunity …

Exploring the “N-Terminal Anchor” Binding Interface of the T3SS Chaperone–Translocator Complexes from P. aeruginosa

CL Frankling, AS Kang, ERG Main - Biochemistry, 2023 - ACS Publications
The type III secretion system is a large multiprotein complex that many Gram-negative
bacteria use for infection. A crucial part of the complex is its translocon pore formed by two …

Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC

M Gárdonyi, C Hasewinkel, J Wallbaum… - ACS …, 2023 - ACS Publications
The Shigella pathogenicity factor IpgC belongs to the class II of type III secretion system
chaperones, whose members are characterized by a tetratricopeptide repeat (TPR) domain …

[HTML][HTML] Exploring the 'N-terminal arm'& 'Convex surface'Binding Interfaces of the T3SS Chaperone-Translocator Complexes from P. Aeruginosa

CL Frankling, MF Downes, AS Kang… - Journal of Molecular …, 2023 - Elsevier
One infection method widely used by many gram-negative bacteria involves a protein
nanomachine called the Type Three Secretion System (T3SS). The T3SS enables the …

α-helices in the type III secretion effectors: A prevalent feature with versatile roles

AD Gazi, M Kokkinidis, VE Fadouloglou - International Journal of …, 2021 - mdpi.com
Type III Secretion Systems (T3SSs) are multicomponent nanomachines located at the cell
envelope of Gram-negative bacteria. Their main function is to transport bacterial proteins …

[PDF][PDF] A Tale about Shigella: Evolution, Plasmid, and Virulence. Microorganisms 2023, 11, 1709

N Haidar-Ahmad, FO Manigat, N Silué, SM Pontier… - 2023 - academia.edu
Shigella spp. cause hundreds of millions of intestinal infections each year. They target the
mucosa of the human colon and are an important model of intracellular bacterial …

Cloning, expression, purification, and oligomeric characterization of the AopB-C-terminus domain in T3SS Major translocator protein of Aeromonas hydrophila

VS Nguyen, TU Nguyen - VNU Journal of Science: Natural Sciences …, 2021 - js.vnu.edu.vn
Type three secretion system (T3SS) is found exclusively in gram-negative pathogens such
as Yersinia spp., Escherichia coli, Salmonella spp., Shigella spp., Pseudomonas spp., Vibrio …