The peroxisome proliferator-activated receptor (PPAR) family includes three transcription
factors: PPARα, PPARβ/δ, and PPARγ. PPAR are nuclear receptors activated by oxidised …

The nuclear factor kB (NF-kB) comprises a family of transcription factors involved in the
regulation of a wide variety of biological responses. NF-kB plays a well-known function in …

Curcumin, the phytochemical component in turmeric, is used as a dietary spice and a topical
ointment for the treatment of inflammation in India for centuries. Curcumin …

In mammals, peroxisomes perform crucial functions in cellular metabolism, signalling and
viral defense which are essential to the health and viability of the organism. In order to …

The peroxisome proliferator-activated receptor PPAR-γ is one of three PPAR nuclear
receptors that act as ligand-activated transcription factors. In immune cells, the skin, and …

Agonists of the peroxisome proliferator activated receptor gamma (PPARγ) are currently
used for treatment of type 2 diabetes due to their insulin sensitizing and glucose metabolism …

Peroxisome proliferator–activated receptor (PPAR)-γ is required for adipogenesis but is also
found in the cardiovascular system, where it has been proposed to oppose inflammatory …

Peroxisome proliferator-activated receptor γ (PPARγ) has been proposed as a therapeutic
target for neurodegenerative diseases because of its anti-inflammatory action in glial cells …

Alzheimer's disease is a complex neurodegenerative disorder, with aging, genetic and
environmental factors contributing to its development and progression. The complexity of …

Background Bisphenol A (BPA), a chemical used as a plasticizer, is a potent endocrine
disruptor that, even in low concentrations, disturbs normal development and functions of …