Organization, dynamics and mechanoregulation of integrin-mediated cell–ECM adhesions

P Kanchanawong, DA Calderwood - Nature Reviews Molecular Cell …, 2023 - nature.com
The ability of animal cells to sense, adhere to and remodel their local extracellular matrix
(ECM) is central to control of cell shape, mechanical responsiveness, motility and signalling …

Nanoscale mechanobiology of cell adhesions

S Xia, P Kanchanawong - Seminars in cell & developmental biology, 2017 - Elsevier
Proper physiological functions of cells and tissues depend upon their abilities to sense,
transduce, integrate, and generate mechanical and biochemical signals. Although such …

Molecular organization of integrin-based adhesion complexes in mouse embryonic stem cells

S Xia, EKF Yim, P Kanchanawong - ACS Biomaterials Science & …, 2019 - ACS Publications
The mechanical microenvironment serves as an important factor influencing stem cell
differentiation. Mechanobiological responses depend strongly on actomyosin contractility …

Nanoscale Structural Organization of Integrin-Based Adhesion Complexes and Actin Cytoskeleton in Mouse Embryonic Stem Cells

X Shumin - 2018 - search.proquest.com
Mechanical cues influence pluripotent stem cell differentiation but the underlying
mechanisms are not well understood. Mouse embryonic stem cells (mESCs) exhibit unusual …