Biological sequence classification: A review on data and general methods

C Ao, S Jiao, Y Wang, L Yu, Q Zou - Research, 2022 - spj.science.org
With the rapid development of biotechnology, the number of biological sequences has
grown exponentially. The continuous expansion of biological sequence data promotes the …

[HTML][HTML] AI applications in functional genomics

C Caudai, A Galizia, F Geraci, L Le Pera… - Computational and …, 2021 - Elsevier
We review the current applications of artificial intelligence (AI) in functional genomics. The
recent explosion of AI follows the remarkable achievements made possible by “deep …

AcrPred: A hybrid optimization with enumerated machine learning algorithm to predict Anti-CRISPR proteins

FY Dao, ML Liu, W Su, H Lv, ZY Zhang, H Lin… - International journal of …, 2023 - Elsevier
CRISPR-Cas, as a tool for gene editing, has received extensive attention in recent years.
Anti-CRISPR (Acr) proteins can inactivate the CRISPR-Cas defense system during …

Anticancer peptides prediction with deep representation learning features

Z Lv, F Cui, Q Zou, L Zhang, L Xu - Briefings in bioinformatics, 2021 - academic.oup.com
Anticancer peptides constitute one of the most promising therapeutic agents for combating
common human cancers. Using wet experiments to verify whether a peptide displays …

Attention-based multi-label neural networks for integrated prediction and interpretation of twelve widely occurring RNA modifications

Z Song, D Huang, B Song, K Chen, Y Song… - Nature …, 2021 - nature.com
Recent studies suggest that epi-transcriptome regulation via post-transcriptional RNA
modifications is vital for all RNA types. Precise identification of RNA modification sites is …

Computational prediction and interpretation of cell-specific replication origin sites from multiple eukaryotes by exploiting stacking framework

L Wei, W He, A Malik, R Su, L Cui… - Briefings in …, 2021 - academic.oup.com
Origins of replication sites (ORIs), which refers to the initiative locations of genomic DNA
replication, play essential roles in DNA replication process. Detection of ORIs' distribution in …

iRNA-ac4C: a novel computational method for effectively detecting N4-acetylcytidine sites in human mRNA

W Su, XQ Xie, XW Liu, D Gao, CY Ma, H Zulfiqar… - International Journal of …, 2023 - Elsevier
Abstract RNA N4-acetylcytidine (ac4C) is the acetylation of cytidine at the nitrogen-4
position, which is a highly conserved RNA modification and involves a variety of biological …

Predicting RNA 5‐Methylcytosine Sites by Using Essential Sequence Features and Distributions

L Chen, ZD Li, SQ Zhang, YH Zhang… - BioMed Research …, 2022 - Wiley Online Library
Methylation is one of the most common and considerable modifications in biological systems
mediated by multiple enzymes. Recent studies have shown that methylation has been …

Identification of sub-Golgi protein localization by use of deep representation learning features

Z Lv, P Wang, Q Zou, Q Jiang - Bioinformatics, 2020 - academic.oup.com
Abstract Motivation The Golgi apparatus has a key functional role in protein biosynthesis
within the eukaryotic cell with malfunction resulting in various neurodegenerative diseases …

[HTML][HTML] Identification of cyclin protein using gradient boost decision tree algorithm

H Zulfiqar, SS Yuan, QL Huang, ZJ Sun, FY Dao… - Computational and …, 2021 - Elsevier
Cyclin proteins are capable to regulate the cell cycle by forming a complex with cyclin-
dependent kinases to activate cell cycle. Correct recognition of cyclin proteins could provide …