[HTML][HTML] The use of selective estrogen receptor modulators on bone health in men
Selective estrogen receptor modulators (SERMs) represent a class of drugs that act as
agonist or antagonist for estrogen receptor in a tissue-specific manner. The SERMs drugs …
agonist or antagonist for estrogen receptor in a tissue-specific manner. The SERMs drugs …
Synthesis and biological evaluation of novel benzothiophene derivatives
Benzothiophene derivatives were synthesized regioselectively using coupling reactions and
electrophilic cyclization reactions. Antimicrobial properties of isolated compounds were …
electrophilic cyclization reactions. Antimicrobial properties of isolated compounds were …
Raloxifene administration enhances retention in an orthodontic relapse model
Background and objectives Orthodontic relapse is a physiologic process that involves
remodelling of the alveolar bone and principle periodontal ligament fibres. Raloxifene is an …
remodelling of the alveolar bone and principle periodontal ligament fibres. Raloxifene is an …
Zoledronate and Raloxifene combination therapy enhances material and mechanical properties of diseased mouse bone
Current interventions to reduce skeletal fragility are insufficient at enhancing both the
quantity and quality of bone when attempting to improve overall mechanical integrity …
quantity and quality of bone when attempting to improve overall mechanical integrity …
Synthesis, X-ray Single Crystal, Conformational Analysis and Cholinesterase Inhibitory Activity of a New Spiropyrrolidine Scaffold Tethered Benzo[b]Thiophene …
Described herein is a one-pot protocol for the synthesis of a substituted spiropyrrolidine
scaffold tethered benzo [b] thiophene analogue from (E)-3-(benzo [b] thiophen-2-yl)-1-(4 …
scaffold tethered benzo [b] thiophene analogue from (E)-3-(benzo [b] thiophen-2-yl)-1-(4 …
Combining anabolic loading and raloxifene improves bone quantity and some quality measures in a mouse model of osteogenesis imperfecta
Osteogenesis imperfecta (OI) increases fracture risk due to changes in bone quantity and
quality caused by mutations in collagen and its processing proteins. Current therapeutics …
quality caused by mutations in collagen and its processing proteins. Current therapeutics …
New strategy for the synthesis of 3-ethynyl-2-(thiophen-2-yl) benzo [b] thiophene derivatives
Pd-catalyzed coupling reactions like the Sonogashira coupling reaction are very useful tools
for the formation of new carbon–carbon bonds under mild reaction conditions. Coupling …
for the formation of new carbon–carbon bonds under mild reaction conditions. Coupling …
A Synthetic Peptide, CK2. 3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
J Nguyen, S Kelly, R Wood, B Heubel… - Journal of Developmental …, 2020 - mdpi.com
The skeletal system plays an important role in the development and maturation process.
Through the bone remodeling process, 10% of the skeletal system is renewed every year …
Through the bone remodeling process, 10% of the skeletal system is renewed every year …
Zoledronate reduces loading-induced microdamage in cortical ulna of ovariectomized rats
As a daily physiological mechanism in bone, microdamage accumulation dissipates energy
and helps to prevent fractures. However, excessive damage accumulation might bring …
and helps to prevent fractures. However, excessive damage accumulation might bring …
Synthesis and Biological Evaluation of Some Polycyclic Aromatic Hydrocarbons
C Kumari, N Dhanda, NK Jangid, S Kumar - S-Heterocycles: Synthesis …, 2024 - Springer
Organic pollutants known as polycyclic aromatic hydrocarbons (PAHs) are produced
primarily when organic materials like oil, gas, and coal are not completely burned. There is a …
primarily when organic materials like oil, gas, and coal are not completely burned. There is a …