Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Biomedical applications of NIR-II organic small molecule fluorescent probes in different organs

L Xu, Q Zhang, X Wang, W Lin - Coordination Chemistry Reviews, 2024 - Elsevier
The optimal functioning of body organs is fundamental to maintaining physiological
processes and bodily health. However, a myriad of factors, including inherent and …

An NIR Fluorescence Turn‐on and MRl Bimodal Probe for Concurrent Real‐time in vivo Sensing and Labeling of β‐Galactosidase

Q Yu, L Zhang, M Jiang, L Xiao, Y Xiang… - Angewandte …, 2023 - Wiley Online Library
To realize sensing and labeling biomarkers is quite challenging in terms of designing
multimodal imaging probes. In this study, we developed a novel β‐galactosidase (β‐gal) …

pH-Responsive NIR-II phototheranostic agents for in situ tumor vascular monitoring and combined anti-vascular/photothermal therapy

S Bian, X Zheng, W Liu, Z Gao, Y Wan, J Li, H Ren… - Biomaterials, 2023 - Elsevier
Developing nanoplatforms integrating superior fluorescence imaging ability in second near-
infrared (NIR-II) window and tumor microenvironment responsive multi-modal therapy holds …

Two Key Descriptors for Designing Second Near-Infrared Dyes and Experimental Validation

Y Zeng, J Qu, G Wu, Y Zhao, J Hao… - Journal of the …, 2024 - ACS Publications
Second near-infrared (NIR-II) optical imaging technology has emerged as a powerful tool for
diagnostic and image-guided surgery due to its higher imaging contrast. However, a general …

Recent advances in the design and applications of near-infrared II responsive small molecule phototherapeutic agents

D Ma, H Bian, M Gu, L Wang, X Chen… - Coordination Chemistry …, 2024 - Elsevier
NIR-II phototherapeutic agents possess the advantages of NIR-II optical imaging and
phototherapy, which include high signal-to-noise ratio imaging and non-invasive treatment …

Imaging gastrointestinal damage due to acute mercury poisoning using a mitochondria-targeted dual near-infrared fluorescent probe

J Zhou, J Li, X Xu, S Long, N Cui, Y Zhang, L Shi… - Journal of Hazardous …, 2024 - Elsevier
Mercury (Hg) is one of the most widespread pollutants that pose serious threats to public
health and the environment. People are inevitably exposed to Hg via different routes, such …

Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

L Zhang, C Yan, Y Zhang, D Ma, J Huang… - Chemical …, 2023 - pubs.rsc.org
Herein, we design a novel “crossbreeding” dye (BC-OH) within the second near-infrared
(NIR-II) window based on BODIPY and chromene chromophores. BC-OH can serve as a …

A Small-Molecule Fluorescent Probe for the Detection of Mitochondrial Peroxynitrite

H Dong, MY Tang, S Shen, XQ Cao, XF Zhang - Molecules, 2023 - mdpi.com
Reactive oxygen species (ROS) are pivotal signaling molecules that control a variety of
physiological functions. As a member of the ROS family, peroxynitrite (ONOO−) possesses …

Water-soluble AIE photosensitizer in short-wave infrared region for albumin-enhanced and self-reporting phototheranostics

Y Xu, J Zhang, Z Wang, P Zhang, Z Zhang, Z Yang… - Biomaterials, 2025 - Elsevier
Organic photosensitizers (PSs) play important roles in phototheranostics, and contribute to
the fast development of precision medicine. However, water-soluble and highly emissive …