The role of inflammation in CKD
SP Kadatane, M Satariano, M Massey, K Mongan… - Cells, 2023 - mdpi.com
Chronic kidney disease (CKD) affects many adults worldwide. Persistent low-grade
inflammation is a substantial factor in its development and progression and has correlated …
inflammation is a substantial factor in its development and progression and has correlated …
Role of MCP-1 as an inflammatory biomarker in nephropathy
Y Liu, K Xu, Y Xiang, B Ma, H Li, Y Li, Y Shi… - Frontiers in …, 2024 - frontiersin.org
The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2
(CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of …
(CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of …
[HTML][HTML] KIM-1 augments hypoxia-induced tubulointerstitial inflammation through uptake of small extracellular vesicles by tubular epithelial cells
J Chen, TT Tang, JY Cao, ZL Li, X Zhong, Y Wen… - Molecular Therapy, 2023 - cell.com
Tubular epithelial cells (TECs) exposed to hypoxia incite tubulointerstitial inflammation (TII),
while the exact mechanism is unclear. In this study, we identified that hypoxia evoked tubule …
while the exact mechanism is unclear. In this study, we identified that hypoxia evoked tubule …
Plasma and urine biomarkers of CKD: a review of findings in the CKiD study
I Sandokji, JH Greenberg - Seminars in nephrology, 2021 - Elsevier
Serum creatinine and level of proteinuria, as biomarkers of chronic kidney disease (CKD)
progression, inadequately explain the variability of glomerular filtration rate decline, and are …
progression, inadequately explain the variability of glomerular filtration rate decline, and are …
Neonatal multimorbidity and the phenotype of premature aging in preterm infants
Multimorbidity is the co-occurrence of multiple chronic health problems, associated with
aging, frailty, and poor functioning. Children born preterm experience more multimorbid …
aging, frailty, and poor functioning. Children born preterm experience more multimorbid …
Urinary DKK3 as a biomarker for short-term kidney function decline in children with chronic kidney disease: an observational cohort study
T Speer, SJ Schunk, T Sarakpi, D Schmit… - The Lancet Child & …, 2023 - thelancet.com
Background Childhood-onset chronic kidney disease is a progressive condition that can
have a major effect on life expectancy and quality. We evaluated the usefulness of the …
have a major effect on life expectancy and quality. We evaluated the usefulness of the …
Risk of chronic kidney disease in children who developed acute kidney injury secondary to nephrotoxic medication exposure in infancy
P Ameta, C Stoops, DJ Askenazi - Renal Failure, 2023 - Taylor & Francis
Introduction Nephrotoxic medication (NTM) is one of the common causes of acute kidney
injury (AKI) in critically ill infants. Current knowledge about the long-term effects of NTM …
injury (AKI) in critically ill infants. Current knowledge about the long-term effects of NTM …
[HTML][HTML] Deceased donor urinary Dickkopf-3 associates with future allograft function following kidney transplantation
J de Fallois, A Günzel, C Daniel, J Stumpf… - American Journal of …, 2024 - Elsevier
Predicting future kidney allograft function is challenging. Novel biomarkers, such as urinary
Dickkopf-3 (uDKK3), may help guide donor selection and improve allograft outcomes. In this …
Dickkopf-3 (uDKK3), may help guide donor selection and improve allograft outcomes. In this …
The Role of Inflammation in CKD
PK Saurav, M Satariano, M Massey, K Mongan… - Cells, 2023 - search.proquest.com
Chronic kidney disease (CKD) affects many adults worldwide. Persistent low-grade
inflammation is a substantial factor in its development and progression and has correlated …
inflammation is a substantial factor in its development and progression and has correlated …
associations of biomarkers of kidney tubule health, injury, and inflammation with left ventricular hypertrophy in children with CKD
K Jiang, JH Greenberg, A Abraham, Y Xu… - Kidney360, 2023 - journals.lww.com
Background Left ventricular hypertrophy (LVH) is common in children with CKD and is
associated with an increased risk of cardiovascular disease and mortality. We have shown …
associated with an increased risk of cardiovascular disease and mortality. We have shown …