Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

The objective of this study was to evaluate the evidence on cost‐effectiveness of
pharmacogenetic (PGx)–guided treatment for drugs with Clinical Pharmacogenetics …

The field of pharmacogenomics (PGx) is gradually shifting from the reactive testing of single
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …

Pharmacogenomics is the use of genomic and other “omic” information to individualize drug
selection and drug use to avoid adverse drug reactions and to maximize drug efficacy. The …

Importance Implementation of pharmacogenetic testing to guide drug prescribing has
potential to improve drug response and prevent adverse events. Robust data exist for more …

People differ in their requirements for and responses to nutrients and bioactive molecules in
the diet. Many inputs contribute to metabolic heterogeneity (including variations in genetics …

Pharmacogenomics, ie, the study of how an individual's genomic profile influences his or her
response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants …

Purpose To examine the evidence on the cost-effectiveness of implementing
pharmacogenomics (PGx) in cardiovascular disease (CVD) care. Methods We conducted a …

Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

In psychiatry, the selection of antipsychotics and antidepressants is generally led by a trial-
and-error approach. The prescribing of these medications is complicated by sub-optimal …