Amygdala-cortical collaboration in reward learning and decision making

KM Wassum - Elife, 2022 - elifesciences.org
Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. These mental simulations are …

Pathways to the persistence of drug use despite its adverse consequences

GP McNally, P Jean-Richard-dit-Bressel… - Molecular …, 2023 - nature.com
The persistence of drug taking despite its adverse consequences plays a central role in the
presentation, diagnosis, and impacts of addiction. Eventual recognition and appraisal of …

The role of the lateral orbitofrontal cortex in creating cognitive maps

KM Costa, R Scholz, K Lloyd, P Moreno-Castilla… - Nature …, 2023 - nature.com
We use mental models of the world—cognitive maps—to guide behavior. The lateral
orbitofrontal cortex (lOFC) is typically thought to support behavior by deploying these maps …

Distinct cortical–amygdala projections drive reward value encoding and retrieval

M Malvaez, C Shieh, MD Murphy, VY Greenfield… - Nature …, 2019 - nature.com
The value of an anticipated rewarding event is a crucial component of the decision to
engage in its pursuit. But little is known of the networks responsible for encoding and …

The mouse prefrontal cortex: Unity in diversity

P Le Merre, S Ährlund-Richter, M Carlén - Neuron, 2021 - cell.com
The prefrontal cortex (PFC) is considered to constitute the highest stage of neural integration
and to be devoted to representation and production of actions. Studies in primates have laid …

A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories

AC Sias, AK Morse, S Wang, VY Greenfield… - Elife, 2021 - elifesciences.org
Adaptive reward-related decision making often requires accurate and detailed
representation of potential available rewards. Environmental reward-predictive stimuli can …

The ventrolateral prefrontal cortex is part of the modular working memory system: A functional neuroanatomical perspective

O Segal, O Elkana - Frontiers in Neuroanatomy, 2023 - frontiersin.org
For many years, the functional role of the ventrolateral Pre-Frontal Cortex (PFC) was
associated with executive functions, specifically in the context of non-affective cognitive …

Orbitofrontal cortex populations are differentially recruited to support actions

C Cazares, DC Schreiner, ML Valencia, CM Gremel - Current Biology, 2022 - cell.com
The ability to use information from one's prior actions is necessary for decision-making.
While orbitofrontal cortex (OFC) has been hypothesized as key for inferences made using …

Prefrontal regulation of behavioural control: evidence from learning theory and translational approaches in rodents

KM Turner, SL Parkes - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Everyday activities require adaptive decision-making and control over our actions to achieve
our goals. Sub-regions within the cortex are widely reported to regulate these choices. Here …

Roles of the prefrontal cortex in learning to time the onset of pre-existing motor programs

BC Lee, J Choi, BJ Martin - PloS one, 2020 - journals.plos.org
The prefrontal cortex (PFC) is involved in cognitive control of motor activities and timing of
future intensions. This study investigated the cognitive control of balance recovery in …