Mechanisms of mechanotransduction and physiological roles of PIEZO channels
B Xiao - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Mechanical force is an essential physical element that contributes to the formation and
function of life. The discovery of the evolutionarily conserved PIEZO family, including PIEZO1 …
function of life. The discovery of the evolutionarily conserved PIEZO family, including PIEZO1 …
[HTML][HTML] Vagal sensory neurons mediate the Bezold–Jarisch reflex and induce syncope
Visceral sensory pathways mediate homeostatic reflexes, the dysfunction of which leads to
many neurological disorders. The Bezold–Jarisch reflex (BJR), first described, in 1867, is a …
many neurological disorders. The Bezold–Jarisch reflex (BJR), first described, in 1867, is a …
[HTML][HTML] Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch
Across mammalian skin, structurally complex and diverse mechanosensory end organs
respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces …
respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces …
Tactile mechanisms and afferents underlying the rat pup transport response
Z Ni, C Neifert, A Rosete, AM Albeely, Y Yang… - Current Biology, 2024 - cell.com
Juvenile rodents and other altricial mammals react with calming, immobility, and postural
modifications to parental pickup, a set of behaviors referred to as the transport response. 1 …
modifications to parental pickup, a set of behaviors referred to as the transport response. 1 …
[HTML][HTML] Immunohistochemical detection of PIEZO1 and PIEZO2 in human digital Meissner´ s corpuscles
Y García-Mesa, P Cuendias, M Alonso-Guervós… - Annals of Anatomy …, 2024 - Elsevier
Background The cutaneous end organ complexes or cutaneous sensory corpuscles are
specialized sensory organs associated to low-threshold mechanoreceptors. Mechano-gated …
specialized sensory organs associated to low-threshold mechanoreceptors. Mechano-gated …
Mechanosensitive Piezo channels and their potential roles in peripheral auditory perception
Z Yi, G Yin, C Wei, Y Quan, Y Sun - Brain‐X, 2024 - Wiley Online Library
Hearing sound and responding to external and internal mechanical stimuli requires specific
proteins as mechanotransducers that convert mechanical forces into biological signals …
proteins as mechanotransducers that convert mechanical forces into biological signals …
Neurophysiology, Neuro-Immune Interactions, and Mechanobiology in Osteopathy in the Cranial Field: An Evidence-Informed Perspective for a Scientific Rationale
N Barsotti, A Casini, M Chiera, C Lunghi, M Fornari - Healthcare, 2023 - mdpi.com
(1) Background: Osteopathy in the cranial field (OCF) is a distinctive approach within
osteopathy, focusing on the cranial region's manual manipulation. Nevertheless, OCF …
osteopathy, focusing on the cranial region's manual manipulation. Nevertheless, OCF …
[HTML][HTML] Multi-needle blow-spinning technique for fabricating collagen nanofibrous nerve guidance conduit with scalable productivity and high performance
CY Yang, Z Hou, P Hu, C Li, Z Li, Z Cheng, S Yang… - Materials Today Bio, 2024 - Elsevier
Nerve guidance conduits (NGCs) have been widely accepted as a promising strategy for
peripheral nerve regeneration. Fabricating ideal NGCs with good biocompatibility …
peripheral nerve regeneration. Fabricating ideal NGCs with good biocompatibility …
The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria
OO Ojewunmi, TA Adeyemo, AI Oyetunji… - Human Molecular …, 2024 - academic.oup.com
The clinical severity of sickle cell disease (SCD) is strongly influenced by the level of fetal
haemoglobin (HbF) persistent in each patient. Three major HbF loci (BCL11A, HBS1L-MYB …
haemoglobin (HbF) persistent in each patient. Three major HbF loci (BCL11A, HBS1L-MYB …
A functional unbalance of TRPM8 and Kv1 channels underlies orofacial cold allodynia induced by peripheral nerve damage
R Piña, G Ugarte, C Guevara, R Pino… - Frontiers in …, 2024 - frontiersin.org
Cold allodynia is a debilitating symptom of orofacial neuropathic pain resulting from
trigeminal nerve damage. The molecular and neural bases of this sensory alteration are still …
trigeminal nerve damage. The molecular and neural bases of this sensory alteration are still …