Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

L Galluzzi, J Humeau, A Buqué, L Zitvogel… - Nature reviews Clinical …, 2020 - nature.com
Conventional chemotherapeutics have been developed into clinically useful agents based
on their ability to preferentially kill malignant cells, generally owing to their elevated …

Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

W Li, J Yang, L Luo, M Jiang, B Qin, H Yin… - Nature …, 2019 - nature.com
Immunogenic cell death (ICD)-associated immunogenicity can be evoked through reactive
oxygen species (ROS) produced via endoplasmic reticulum (ER) stress. In this study, we …

Wogonin and its analogs for the prevention and treatment of cancer: A systematic review

K Banik, E Khatoon, C Harsha, V Rana… - Phytotherapy …, 2022 - Wiley Online Library
The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …

Natural products and their derivatives: Promising modulators of tumor immunotherapy

LJ Deng, M Qi, N Li, YH Lei, DM Zhang… - Journal of Leucocyte …, 2020 - academic.oup.com
A wealth of evidence supports the role of tumor immunotherapy as a vital therapeutic option
in cancer. In recent decades, accumulated studies have revealed the anticancer activities of …

Cell death and immunity in cancer: from danger signals to mimicry of pathogen defense responses

AD Garg, P Agostinis - Immunological reviews, 2017 - Wiley Online Library
The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond developing immunostimulatory regimens like dendritic cell‐based …

Consensus guidelines for the detection of immunogenic cell death

O Kepp, L Senovilla, I Vitale, E Vacchelli… - …, 2014 - Taylor & Francis
Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …

Molecular and translational classifications of DAMPs in immunogenic cell death

AD Garg, L Galluzzi, L Apetoh, T Baert… - Frontiers in …, 2015 - frontiersin.org
The immunogenicity of malignant cells has recently been acknowledged as a critical
determinant of efficacy in cancer therapy. Thus, besides developing direct …

[PDF][PDF] Immunogenic cell death.

AD Garg, AM Dudek-Peric, E Romano… - International Journal of …, 2015 - researchgate.net
Currently, it is widely acknowledged that a proactive anticancer immunosurveillance
mechanism takes part in the rejection of neoplastic lesions before they progress towards a …

Natural products and their derivatives as immune check point inhibitors: Targeting cytokine/chemokine signalling in cancer

M Gupta, K Chandan, M Sarwat - Seminars in cancer biology, 2022 - Elsevier
Cancer immunotherapy is the new generation and widely accepted form of tumour
treatment. It is, however, associated with exclusive challenges which include organ-specific …