The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

K Bedard, KH Krause - Physiological reviews, 2007 - journals.physiology.org
For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Review Biologically active products of stimulated liver macrophages (Kupffer cells)

K Decker - EJB Reviews 1990, 1990 - Springer
Macrophages belong to the mononuclear phagocyte system that includes the blood
monocytes and the various kinds of mobile and sessile macrophages. They are recruited …

[PDF][PDF] Kupffer cell activation and endothelial cell damage after storage of rat livers: effects of reperfusion

JC Caldwell‐Kenkel, RT Currin, Y Tanaka… - …, 1991 - Wiley Online Library
Reperfusion injury characterized by loss of endothelial cell viability occurs after cold
ischemic storage of livers for transplantation surgery. Here, ultrastructural changes in stored …

Oxygen-derived free radicals promote hepatic injury in the rat

MJP Arthur, IS Bentley, AR Tanner, PK Saunders… - Gastroenterology, 1985 - Elsevier
We have investigated the possible protective effect of Superoxide dismutase and allopurinol
in a rat model of mild and severe hepatic necrosis produced by Corynebacterium parvum …

Cell biology and kinetics of Kupffer cells in the liver

K Wake, K Decker, A Kirn, DL Knook… - International review of …, 1989 - Elsevier
Publisher Summary The study of Kupffer cells has developed rapidly and has been
extended to problems concerning the origin, structure, and function of these cells in normal …

[图书][B] Copper Proteins and Copper Enzymes: Volume II

R Lontie - 2018 - taylorfrancis.com
These volumes of Copper Proteins and Copper Enzymes are intended to describe the
contemporary spectroscopy and other biophysical chemistry now being applied to copper …

Mechanisms of hepatocellular dysfunction and regeneration: Enzyme inhibition by nitroimidazole and human liver regeneration

R Sharma - Enzyme inhibition and bioapplications, 2012 - books.google.com
Enzymes so called (Enz'-a-ai-am) are biologically active protein molecules responsible of
biochemical reactions in the bacteria, cells and organs. Enzymes regulate the rates of …

Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates.

DA Lepay, CF Nathan, RM Steinman… - The Journal of …, 1985 - rupress.org
Murine Kupffer cells (KC) were isolated by a high yield collagenase perfusion technique.
The morphology, surface markers, and secretory products were typical of macrophages in …

Scientific basis for the clinical use of superoxide dismutase

A Petkau - Cancer Treatment Reviews, 1986 - Elsevier
In a recent review of chemical carcinogenesis, Kensler and Trush (157) express the hope
'that an evaluation of the importance of oxygen free radicals in chemical carcinogenesis will …

Beyond bacterial killing: NADPH oxidase 2 is an immunomodulator

SC Trevelin, AM Shah, G Lombardi - Immunology Letters, 2020 - Elsevier
NADPH oxidase 2 is a superoxide-generating enzymatic complex based on the catalytic
subunit gp91phox that is also known as Nox2. Initially identified in neutrophils, NADPH …