The budding yeast Saccharomyces cerevisiae has been the principal organism used in
experiments to examine genetic recombination in eukaryotes. Studies over the past decade …

DNA double-strand breaks (DSB) are considered to be critical primary lesions in the
formation of chromosomal aberrations. DSB may be induced by exogenous agents, such as …

This treatise is an update to a preceding highlight (CH/π hydrogen bonds in crystals)
published in this journal 5 years ago (M. Nishio, CrystEngComm, 2004, 6, 130–156). After …

Chromosomal double-strand breaks (DSBs) arise after exposure to ionizing radiation or
enzymatic cleavage, but especially during the process of DNA replication itself. Homologous …

The stability of DNA ends generated by the HO endonuclease in yeast is surprisingly high
with a half-life of more than an hour. This transient stability is unaffected by mutations that …

Homologous recombination (HR) uses a homologous template to accurately repair DNA
double-strand breaks and stalled replication forks to maintain genome stability. During …

An open question in meiosis is whether the Rad51 recombination protein functions solely in
meiotic recombination or whether it is also involved in the chromosome homology search …

Crystal structures deposited in the Cambridge Structural Database (CSD) were examined,
by use of our program CHPI, for several kinds of clathrates in order to know the role of the …

Computer-simulated elongation and compression of A-and B-DNA structures beyond the
range of thermal fluctuations provide new insights into high energy “activated” forms of DNA …

Rad51 protein forms nucleoprotein filaments on single-stranded DNA (ssDNA) and then
pairs that DNA with the complementary strand of incoming duplex DNA. In apparent contrast …