Until recently, the nucleic acid content of platelets was considered to be fully determined by
their progenitor megakaryocyte. However, it is now well understood that additional …

Platelets play a crucial role in cancer blood metastasis. Various cancer-related factors such
as Toll-like receptors (TLRs), adenosine diphosphate (ADP) or extracellular matrix (ECM) …

Nucleic acids and proteins are shed into the bloodstream by tumor cells and can be
exploited as biomarkers for the detection of cancer. In addition, cancer detection biomarkers …

Gliomas are a heterogenous group of central nervous system tumors with different outcomes
and different therapeutic needs. Glioblastoma, the most common subtype in adults, has a …

Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …

Platelets are a class of pluripotent cells that, in addition to hemostasis and maintaining
vascular endothelial integrity, are also involved in tumor growth and distant metastasis. The …

Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Sarcoma is a heterogeneous group of rare malignancies arising from mesenchymal tissues.
Recurrence rates are high and methods for early detection by blood-based biomarkers do …

Simple Summary Molecular diagnostic tests can facilitate molecular classification of breast
cancer and its clinical management, including prediction, prognosis, and selection of …

Background Most malignant brain gliomas (MBGs) are associated with dismal outcomes,
mainly due to their late diagnosis. Current diagnostic methods for MBGs are based on …