Mitochondrial dysfunction has been implicated in the development of insulin resistance (IR);
however, a large variety of association and intervention studies as well as genetic …

Skeletal muscle possesses dramatic metabolic plasticity that allows for the rapid adaptation
in cellular energy transduction to meet the demands of the organism. Obesity elicits changes …

Members of the PGC‐1 family of coactivators have been revealed as key players in the
regulation of energy metabolism. Early gain‐and loss‐of‐function studies led to the …

Redox-dependent processes influence most cellular functions, such as differentiation,
proliferation, and apoptosis. Mitochondria are at the center of these processes, as …

Exercise training induces mitochondrial biogenesis, but the time course of molecular
sequelae that accompany repetitive training stimuli remains to be determined in human …

Royal jelly (RJ) is a kind of bee product widely used in cosmetics, medicine and other fields.
Not only can RJ regulate the physiological function of bee population, but also play a …

Background Maintaining skeletal muscle mitochondrial content and function is important for
sustained health throughout the lifespan. Exercise stimulates important key stress signals …

Disturbances in fatty acid metabolism in adipose tissue, liver, skeletal muscle, gut and
pancreas play an important role in the development of insulin resistance, impaired glucose …

According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS)
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …

Fatty acids derived from adipose tissue lipolysis, intramyocellular triacylglycerol lipolysis, or
de novo lipogenesis serve a variety of functions in skeletal muscle. The two major fates of …