Bacterial infectious diseases are one of the leading causes of death worldwide. Even with
the use of multiple antibiotic treatment strategies, 4.95 million people died from drug …

Enterococcus faecalis, Enterococcus faecium and Staphylococcus aureus are both common
commensals and major opportunistic human pathogens. In recent decades, these bacteria …

Staphylococcus aureus frequently causes infections that are challenging to treat, leading to
high rates of persistent and relapsing infection. Here, to understand how the host …

The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

Multidrug-resistant bacteria have on overwhelming impact on human health, as they cause
over 670,000 infections and 33,000 deaths annually in the European Union alone. Of these …

The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …

The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Microbial metabolomics focuses on the analysis of intracellular or extracellular primary
metabolites, signaling molecules, hormones, and secondary metabolites, and it is an …

This review provides an analysis of the role that membrane composition and structure plays
in the resistance of microorganisms to antimicrobial peptides (AMPs). We describe the …

The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …