[HTML][HTML] Genome-wide loss of heterozygosity predicts aggressive, treatment-refractory behavior in pituitary neuroendocrine tumors

AL Lin, VA Rudneva, AL Richards, Y Zhang… - Acta …, 2024 - Springer
Pituitary neuroendocrine tumors (PitNETs) exhibiting aggressive, treatment-refractory
behavior are the rare subset that progress after surgery, conventional medical therapies …

The Contribution of Mosaic Chromosomal Alterations to Schizophrenia

K Chang, X Jian, C Wu, C Gao, Y Li, J Chen, B Xue… - Biological …, 2024 - Elsevier
Background Mosaic chromosomal alterations (mCAs) are implicated in neuropsychiatric
disorders, yet the contribution to schizophrenia (SCZ) risk for somatic copy number …

Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer

MJ Williams, MUJ Oliphant, V Au, C Liu, C Baril… - bioRxiv, 2024 - biorxiv.org
Cancer-associated mutations have been documented in normal tissues, but the prevalence
and nature of somatic copy number alterations and their role in tumor initiation and evolution …