Enteric glial biology, intercellular signalling and roles in gastrointestinal disease
L Seguella, BD Gulbransen - Nature reviews Gastroenterology & …, 2021 - nature.com
One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …
many functions normally attributed to enteric neurons involve interactions with enteric glial …
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
Neuro–immune cell units: a new paradigm in physiology
C Godinho-Silva, F Cardoso… - Annual review of …, 2019 - annualreviews.org
The interplay between the immune and nervous systems has been acknowledged in the
past, but only more recent studies have started to unravel the cellular and molecular players …
past, but only more recent studies have started to unravel the cellular and molecular players …
Novel functional roles for enteric glia in the gastrointestinal tract
BD Gulbransen, KA Sharkey - Nature reviews Gastroenterology & …, 2012 - nature.com
Enteric glia are a unique class of peripheral glial cells within the gastrointestinal tract. Major
populations of enteric glia are found in enteric ganglia in the myenteric and submucosal …
populations of enteric glia are found in enteric ganglia in the myenteric and submucosal …
Chemotherapy induced gastrointestinal toxicities
HI Akbarali, KH Muchhala, DK Jessup… - Advances in cancer …, 2022 - Elsevier
Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …
The digestive neuronal–glial–epithelial unit: a new actor in gut health and disease
The monolayer of columnar epithelial cells lining the gastrointestinal tract—the intestinal
epithelial barrier (IEB)—is the largest exchange surface between the body and the external …
epithelial barrier (IEB)—is the largest exchange surface between the body and the external …
Intestinal stem cell niche: the extracellular matrix and cellular components
The intestinal epithelium comprises a monolayer of polarised columnar cells organised
along the crypt‐villus axis. Intestinal stem cells reside at the base of crypts and are …
along the crypt‐villus axis. Intestinal stem cells reside at the base of crypts and are …
Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione
TC Savidge, P Newman, C Pothoulakis, A Ruhl… - Gastroenterology, 2007 - Elsevier
Background & Aims: Barrier functions across epithelia and endothelia are essential for
homeostatic tissue regulation. Astroglia interact with cerebral endothelia to maintain the …
homeostatic tissue regulation. Astroglia interact with cerebral endothelia to maintain the …
Enteric glia regulate gastrointestinal motility but are not required for maintenance of the epithelium in mice
M Rao, D Rastelli, L Dong, S Chiu, W Setlik… - Gastroenterology, 2017 - Elsevier
Background & Aims When the glial fibrillary acidic protein (GFAP) promoter is used to
express cellular toxins that eliminate glia in mice, intestinal epithelial permeability and …
express cellular toxins that eliminate glia in mice, intestinal epithelial permeability and …
Enteric glia: the most alimentary of all glia
V Grubišić, BD Gulbransen - The Journal of physiology, 2017 - Wiley Online Library
Glia (from Greek γλοία meaning 'glue') pertains to non‐neuronal cells in the central (CNS)
and peripheral nervous system (PNS) that nourish neurons and maintain homeostasis. In …
and peripheral nervous system (PNS) that nourish neurons and maintain homeostasis. In …