Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer
Pancreatic cancer (PC) is a fatal disease that has a poor 5-year survival rate. The poor
prognosis can be attributed to both troublesome detections at the initial stage, which makes …
prognosis can be attributed to both troublesome detections at the initial stage, which makes …
The bioengineered and multifunctional nanoparticles in pancreatic cancer therapy: Bioresponisive nanostructures, phototherapy and targeted drug delivery
The multidisciplinary approaches in treatment of cancer appear to be essential in term of
bringing benefits of several disciplines and their coordination in tumor elimination. Because …
bringing benefits of several disciplines and their coordination in tumor elimination. Because …
Enhanced targeting of 3D pancreatic cancer spheroids by aptamer-conjugated polymeric micelles with deep tumor penetration
L Tian, R Pei, L Zhong, Y Ji, D Zhou, S Zhou - European Journal of …, 2021 - Elsevier
Pancreatic cancer is a high degree malignant tumor which makes its diagnosis and
treatment highly critical. The effect of conventional chemotherapy for pancreatic cancer is …
treatment highly critical. The effect of conventional chemotherapy for pancreatic cancer is …
[HTML][HTML] Living cell for drug delivery
Y Wu, Y Liu, T Wang, Q Jiang, F Xu, Z Liu - Engineered Regeneration, 2022 - Elsevier
The living cells have been emerged as useful platforms for drug delivery due to their
advantages of good liquidity, stability, and low immunogenicity. In this review, we …
advantages of good liquidity, stability, and low immunogenicity. In this review, we …
[HTML][HTML] 3'untranslated regions (3'UTR) of Gelsolin mRNA displays anticancer effects in non-small cell lung cancer (NSCLC) cells
X Liu, X Huang, J Ma, L Li, H Hu, J Feng… - American Journal of …, 2021 - ncbi.nlm.nih.gov
RNA-based therapeutics has attracted substantial interest from both academics and
pharmaceutical companies. In this study, we investigated the function and the underlying …
pharmaceutical companies. In this study, we investigated the function and the underlying …
Molecular application of aptamers in the diagnosis and treatment of cancer and communicable diseases
Cancer and infectious diseases such as Ebola, HIV, tuberculosis, Zika, hepatitis, measles
and human schistosomiasis are serious global health hazards. The increasing annual …
and human schistosomiasis are serious global health hazards. The increasing annual …
Multifunctional aptamer grafted targeted nano‐drugs execute molecular cross‐talks with cancer cells
S Manna, R Mahata, SK Dey… - Applied …, 2024 - Wiley Online Library
The biggest obstacles in treating cancer with traditional chemotherapy are unpleasant side
effects and drug resistance. A growing amount of interest has been exhibited in using …
effects and drug resistance. A growing amount of interest has been exhibited in using …
An overview of aptamer: The prominent applications and different computational tools for its design
Background: Aptamers are short single-stranded oligonucleotides; due to their 3D structure,
they can specifically bind to various targets. They can target several molecules ranging from …
they can specifically bind to various targets. They can target several molecules ranging from …
[PDF][PDF] Selection and characterization of an aptamer to a thiazole orange derivative for use in a fluorescence-based biosensor
V La - 2023 - uwspace.uwaterloo.ca
Aptamers are short single-stranded DNA or RNA sequences that have been selected in vitro
to have a high binding affinity to a specific target molecule. One class of aptamers can bind …
to have a high binding affinity to a specific target molecule. One class of aptamers can bind …
AptaBlocks Online: A Web-Based Toolkit for the In Silico Design of Oligonucleotide Sticky Bridges
J Hoinka, Y Wang, TM Przytycka - Journal of Computational Biology, 2020 - liebertpub.com
The AptaBlocks Web Interface is focused on providing graphical, intuitive, and platform-
independent access to AptaBlocks, an experimentally validated algorithmic approach for the …
independent access to AptaBlocks, an experimentally validated algorithmic approach for the …