Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …

[HTML][HTML] Nanomaterials for cancer therapy: current progress and perspectives

Z Cheng, M Li, R Dey, Y Chen - Journal of hematology & oncology, 2021 - Springer
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

[HTML][HTML] Nanostructured lipid carriers for delivery of chemotherapeutics: A review

M Haider, SM Abdin, L Kamal, G Orive - Pharmaceutics, 2020 - mdpi.com
Pharmaceutics | Free Full-Text | Nanostructured Lipid Carriers for Delivery of
Chemotherapeutics: A Review Next Article in Journal Mechanochemical Formation of …

[HTML][HTML] Dependence of nanoparticle toxicity on their physical and chemical properties

A Sukhanova, S Bozrova, P Sokolov… - Nanoscale research …, 2018 - Springer
Studies on the methods of nanoparticle (NP) synthesis, analysis of their characteristics, and
exploration of new fields of their applications are at the forefront of modern nanotechnology …

[HTML][HTML] Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery

A Khosa, S Reddi, RN Saha - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …

[HTML][HTML] Nanostructured lipid carriers: A groundbreaking approach for transdermal drug delivery

I Chauhan, M Yasir, M Verma… - Advanced pharmaceutical …, 2020 - ncbi.nlm.nih.gov
Nanostructured lipid carriers (NLCs) are novel pharmaceutical formulations which are
composed of physiological and biocompatible lipids, surfactants and co-surfactants. Over …

[HTML][HTML] Preparation of solid lipid nanoparticles and nanostructured lipid carriers for drug delivery and the effects of preparation parameters of solvent injection method

VA Duong, TTL Nguyen, HJ Maeng - Molecules, 2020 - mdpi.com
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as
potential drug delivery systems for various applications that are produced from …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …