Antibody-drug conjugates for hepato-pancreato-biliary malignancies:“Magic bullets” to the rescue?
C Theocharopoulos, IA Ziogas, CC Douligeris… - Cancer Treatment …, 2024 - Elsevier
Abstract Hepato-Pancreato-Biliary (HPB) malignancies constitute a highly aggressive group
of cancers that have a dismal prognosis. Patients not amenable to curative intent surgical …
of cancers that have a dismal prognosis. Patients not amenable to curative intent surgical …
Tumor Microenvironment Modulation by Cancer-Derived Extracellular Vesicles
The tumor microenvironment (TME) plays an important role in the process of tumorigenesis,
regulating the growth, metabolism, proliferation, and invasion of cancer cells, as well as …
regulating the growth, metabolism, proliferation, and invasion of cancer cells, as well as …
Covalent conjugation of AZD8055 with unsaturated fatty acids for the development of mTOR nanoblockers: increasing the therapeutic efficacy of hepatocellular …
WK Chau, TKW Lee - Ebiomedicine, 2024 - thelancet.com
In the latest issue of eBioMedicine, Tang et al. utilized a nanotherapeutic approach to
specifically target the mTOR pathway by PEGylating linoleic acid (LNA)-conjugated …
specifically target the mTOR pathway by PEGylating linoleic acid (LNA)-conjugated …
The association between primary hypobetalipoproteinemia and hepatic Diseases: evidence from genetic studies
Y Zhang, J Chen, S Su - Journal of Hepatology, 2024 - journal-of-hepatology.eu
We have taken a keen interest in the recent study by Matthieu Wargny et al. which 14
analyzed data from 34,653 participants in the CONSTANCES (Frence) cohort and 15 94,666 …
analyzed data from 34,653 participants in the CONSTANCES (Frence) cohort and 15 94,666 …
Mapping Heterogeneity of Hepatocellular Carcinoma by Investigating Hepatocyte-Specific Genes/TFs/Pathways Across Cellular and Tumor Landscapes
O Shafi, R Rajpar, S Zafar, S Irfan, M Ashar, SH Jafry… - 2024 - researchsquare.com
Background: Hepatocellular carcinoma (HCC) presents challenges due to tumor
heterogeneity and therapeutic resistance. Understanding the molecular mechanisms driving …
heterogeneity and therapeutic resistance. Understanding the molecular mechanisms driving …
Aptamer selection for assisted treatment of hepatocellular carcinoma
M CASIAN, O HOSU-STANCIOIU… - Book of … - bioanalysis-prague-2024.cz
The main objective of this project was to select a novel aptamer using magnetic-bead
SELEX technology for glypican-3, an HCC biomarker found on the surface of hepatic tumor …
SELEX technology for glypican-3, an HCC biomarker found on the surface of hepatic tumor …